Oral health is mirror of general health. Oral healthcare professionals must be able to identify patients with systemic diseases, compromising conditions, and disabilities that have an impact on, and can be impacted by, oral and maxillofacial health care. The ability to properly practice dentistry within the context of the larger health care system is often a challenge for the dental practitioner but need not be so. Inappropriate identification of a patient with a compromising systemic condition through improper history taking and interpretation, can create ineffective, or even detrimental, oral health care.

A significant aspect of cosmetic dentistry is the treatment of tooth discoloration. Discoloration of non-vital anterior teeth can cause significant esthetic concern and requires efficient treatment. Discoloration of teeth can be extrinsic or intrinsic or a combination of both based on etiology, appearance, localization, and severity. Walking bleach involves the use of chemical substances like sodium perborate or hydrogen peroxide which in contact with the tooth release oxidizing agents that diffuse through the enamel and dentin and oxidize the pigments responsible for discoloration. This article aims at presenting a case series on the walking bleach method performed on discolored endodontically treated teeth associated with superior esthetic outcomes.

Endodontic treatment is challenging in teeth with a blunderbuss canal and an open apex due to difculties in attaining an apical seal. Nonsurgical one-step apexication using materials such as mineral trioxide aggregate has been proposed to overcome the shortcomings of the traditional longterm calcium hydroxide apexication technique. In order to create an apical plug, there has to be some matrix against which MTA can be placed. Platelet-rich brin (PRF), a second-generation platelet concentrate, can be employed as a matrix material against which MTA can be condensed. This case series aims to present the treatment of an immature tooth with an open apex using a one-step apexication using autologous PRF membrane as an interior matrix and MTA as an apical barrier.