Background: Since 2019, the pandemic of Coronavirus disease 2019 (COVID-19) has spread very rapidly in China and Worldwide. COVID-19 is a highly contagious, infectious and rapidly spreading viral disease with an alarming case fatality rate up to 5%. Case Report: In this article, we report a case of 60 years old non diabetic, hypertensive woman infected with COVID-19 who has end stage renal disease (ESRD) on hemodialysis for last 18 months. COVID-19 patients with ESRD need isolation dialysis but most of them cannot be handled properly due to limited hemodialysis machine. With these unavailability and risk, we continue the treatment along with hemodialysis for controlling uraemia and fluid balance. With all effort this patient ended with an uneventful course with clinical improvement, improvement of all laboratory parameters and resolution of radiological findings but follow up RT-PCR cannot done due to changing guideline of discharge criteria of COVID-19 patient in Bangladesh. He positively responded to meropenem, clarithromycin, favipiravir, thromboprophylaxis with enoxaparin along with supplemental oxygen therapy. After that she was discharged with an advice of 14 days home isolation with regular hemodialysis and a follow up visit after 14 days in the outpatient department. Conclusion: An ESRD patient on regular hemodialysis suffering from severe pneumonia has high risk of mortality. Combined effort from the health care workers are needed to decrease the mortality of COVID-19 infected ESRD patients.

Introduction: Acute bronchiolitis is a condition where patients are presenting with breathing difficulties, cough, poor feeding, and irritability. Treatment of bronchiolitis have many controversies. Most trials of bronchiolitis treatment suffer from 2 constraints: possible inclusion of patients with asthma and inconsistent outcome measures. The aim of the study was to determine the efficacy of prednisolone in recovery from acute bronchiolitis who have a family history of atopy. Material & Methods: This randomized double blind placebo controlled trial (RCT) was conducted in the department of pediatrics Dhaka Medical College Hospital (DMCH) from July 2008 to June 2010. Sixty (60) bronchiolitis patients having family history of atopy were included in his study. Prednisolone and placebo were packaged in identical envelops with separate code number given by the guide and the code number were recorded in a preformed questionnaire. The trial was so planned that neither the parents nor the investigator were aware of group allocation. The collected data were analyzed thoroughly by SPSS program version of 16.0 software. Informed written consent from parents or legal guardians was taken and ethical clearance was obtained from the ethical review committee of Dhaka Medical College to conduct the research works. Results: In our study, mean age of the patients of this series were 3.68 months (±1.29SD) and 3.52 month's (±1.1SD) in prednisolone and placebo group respectively. Use of accessory muscle score was assessed twice at 8 am and 8 pm each day for three days. On first assessment at day 1 the score was similar in both the treatment groups (P>.05). More people in Prednisolone arm recovered within 3 days then the placebo group. The difference is statistically significant (P<.01). Conclusion: Three-day oral prednisolone treatment was effective in accelerating clinical recovery (Fast breathing, use of accessory muscle, wheezing) in acute bronchiolitis cases who had family history of atopy.

Purpose:  To measure the Knowledge, Attitude and Practices parents/caregivers about ROP in the rural setting of Bangladesh. Study Design:  Cross-sectional descriptive study. Place and Duration of Study:  Rural area of Bangladesh, from August 2019 to September 2019. Material and Methods:  A total of 80 preterm babies’ parents/caregivers were interviewed. Quantitative data and qualitative data were also collected through 6 Informal Group Discussions and 2 In-depth Interviews. There was a one-day session with all persons involved with the study for clear understanding of the study goal and every item of the format and interview schedule. The study format and interview schedule were given to one social scientist and one public health expert in determining content validity. Their comments were incorporated in finalizing the research instruments. The filled-in formats and interview schedules were edited immediately after the collection. Both quantitative and qualitative data were collected for the study. Results:  The most common risk factor for ROP was oxygen supply (79%), Bio-safety (67%) and weight (66%). The major reasons for not screening for ROP were lack of awareness (84%), lack of knowledge (48%), family related issues (77%), socio-economic condition (78%), distance (55%), frustration (65%) and overconfidence (52%). About 86.4% (CI: 80.3 – 85.2) had faced difficulties to obtain ROP services. We found significant association between facing treatment difficulties/guardian knowledge about ROP and time of age of screening for ROP (p <.001). Conclusion:  The majority of parents/caregivers suggested for ROP screening, and put recommendations to improve mother anti-natal care (ANC) and strongly supported community awareness campaign to reduce the ROP related burden at rural setting.