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Objective: A prospective, observational study in Dhaka Medical College Hospital was carried out to assess the efficacy of loop electrosurgical excision procedure (LEEP) of the transformation zone of cervix as an outpatient procedure as diagnostic and therapeutic purpose during visit of patients with the report of CIN II or CIN III on histopathology.Method: One hundred women over a period of one year from 1st January to 31st December 2011 were treated with LEEP as an outpatient procedure. Among these women 63 patients were CIN II and 37 patients were CIN III on histopathology report. LEEP were done under local anaesthesia. All patients were followed up for one year with colposcopy and also histology where appropriate.Results: In all cases, the specimens obtained were adequate for histopathological assessment and in 98 (98%) cases the lesion had been completely excised. Two cases of CIN III required a second excision. One patient needed cervical sutures to achieve haemostasis following the excision. One patient was admitted in the hospital with primary haemorrhage. Two patients were admitted with secondary haemorrhage.Conclusion: LEEP under local anaesthesia is an effective technique. It enables the treatment of patients with cervical intraepithelial neaplasia and exclusion of invasive cancer in a subsequent visit. Thus adequate tissue is made available for accurate diagnosis, thereby improving the accuracy of treatment.Bangladesh J Obstet Gynaecol, 2012; Vol. 27(1) : 5-8

J Dhaka Medical College, Vol. 21, No. 2, October, 2012, Page 226-228 DOI: http://dx.doi.org/10.3329/jdmc.v21i2.15363

Introduction: Every year millions of people fall sick with Tuberculosis (TB). Multidrug-resistant tuberculosis (MDR-TB) has a life threatening public health crisis globally. Objective: To determine the successful treatment outcomes of MDR-TB in Bangladeshi population. Methods: This retrospective cohort study was conducted at the National Institute of Diseases of the Chest and Hospital (NIDCH) Mohakhali, Dhaka, on 224 patients enrolled within July 2014 to June 2015. Data were collected by face-to-face interview and reviewing medical records. Results: A total of 224 MDR-TB patients’ histories were studied, among them male and female were 71% and 29% respectively. The average age was 37.6± 13.7 years. Of the total MDR-TB patients, 49(21.9%) were successfully treated, 124 (55.4%) had completed, 3(1.3%) had treatment failure, 5(2.2%) were lost to follow-up, 1(0.4%) was XDR-TB and 29 (12.9%) died. This study also found out that the patient with advanced age (≥55;p<0.001), living in rural areas (p<0.01), history of missing dose(p<0.001) and co-morbidity after treatment (p<0.05) were significantly associated with poor treatment outcomes of MDR-TB. Conclusion: The study concluded that the successful treatment outcomes were 77.2% and the mortality rate was 12.9% of MDRTB patients. Living in rural areas and missing dose were significantly associated with poor treatment outcomes. So, the study demonstrated that it is necessary to ensure the completion of whole treatment course to manage TB patients effectively in order to prevent MDR-TB. JAFMC Bangladesh. Vol 18, No 1 (June) 2022: 57-60

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