Nomophobia is an emerging phenomenon in the 21st century. Consequently, it results in various health problems, both physical and psychological. The following systematic review and meta-analysis aimed to establish the relationship between nomophobia with anxiety, smartphone addiction, and insomnia. To identify the relevant studies, we searched through several databases. Out of the 1523 studies identified, 16 studies met the inclusion criteria. After conducting the statistical analysis, the results revealed that anxiety r = 0.31 (95% CI: 0.25 to 0.38), smartphone addiction r = 0.39 (95% CI: 0.04 to 0.75), and insomnia r = 0.56 (95% CI: 0.38 to 0.75) are positively associated with nomophobia. Mobile phone usage has become inevitable, even for individuals who use it to a lesser degree than others, to perform simple tasks, such as communicating with others or for educational purposes. It is crucial to raise awareness about the consequences of overusing these devices, including the physical and psychological complications in both the short and long terms.

Globally, postpartum hemorrhage (PPH) is the top cause of maternal death. Multiple uterotonic medications are available to prevent PPH; however, it is still unclear whether one is the most effective. The current study compared the efficacy and safety of intravenous carbetocin with rectal misoprostol for the active management of the third stage of labor in order to prevent PPH. Eligible studies were found utilizing digital medical sources, including the Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science (WOS), PubMed, Scopus, and Google Scholar, from inception until September 2022. Only randomized controlled trials (RCTs) that matched the inclusion requirements were chosen. We used the Cochrane Risk of Bias scale (version 2) to assess the quality of the included studies. The Review Manager (version 5.4 for Windows) was used to conduct the meta-analysis. The results were summarized as mean difference (MD) or risk ratio (RR) with a 95% confidence interval (CI) in fixed- or random-effects models according to the degree of between-study heterogeneity. Collectively, we screened 621 articles after omitting duplicates and eventually included three RCTs for analysis. Overall, 404 patients were included in these studies; 202 patients were allocated to the intravenous carbetocin group whereas 202 patients were allocated to the rectal misoprostol group. Two RCTs were judged as “low” risk of bias, whereas one RCT was judged as having “some concerns” regarding the quality assessment. Regarding efficacy endpoints, the intravenous carbetocin group had significantly lower blood loss (n=3 RCTs, MD=-117.74 mL, 95% CI [-185.41, -50.07], p<0.001), need for additional uterotonics (n=2 RCTs, RR=0.06, 95% CI [0.01, 0.46], p=0.007), need for uterine massage (n=2 RCTs, RR=0.40, 95% CI [0.20, 0.80], p=0.009), and need for blood transfusion (n=2 RCTs, RR=0.38, 95% CI [0.15, 0.95], p=0.04) compared with the rectal misoprostol group. Regarding safety endpoints, the rates of diarrhea (n=3 RCTs, RR=0.18, 95% CI [0.06, 0.55], p=0.003) and chills (n=2 RCTs, RR=0.31, 95% CI [0.12, 0.83], p=0.02) were significantly lower in the intravenous carbetocin group compared with the rectal misoprostol group. However, there was no significant difference between both groups regarding the rates of headache (n=3 RCTs, RR=1.23, 95% CI [0.06, 1.91], p=0.35) and facial flushing (n=2 RCTs, RR=0.88, 95% CI [0.46, 1.68], p=0.70). In conclusion, it was discovered that intravenous carbetocin was a superior substitute for rectal misoprostol for the active management of the third stage of labor. With far fewer side effects, intravenous carbetocin decreased postpartum blood loss and further uterotonic use. For women who have a high risk of PPH, intravenous carbetocin is advised.

Acne vulgaris usually affects the dermal layer of the skin and is revealed frequently in young adulthood and adolescence. It has serious psychosocial comorbidities. We conducted the present systematic review and meta-analysis to elucidate the association of acne vulgaris with psychiatric comorbidities and quality of life as well as the brain-derived neurotrophic factor (BDNF) level. A systematic review and meta-analysis of the published articles were carried out following the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. We investigated diverse databases: Web of Science, PubMed, the Cochrane Library, Embase, PsycINFO, and CINAHL to search for articles reporting the prevalence of psychosocial comorbidities among patients with acne vulgaris from database inception through June 2022. The outcomes were depression, anxiety, symptom checklist-90-R (SCL-90-R), quality of life, self-esteem, stress, loneliness, and BDNF concentrations. Of 3647 articles identified, 23 met the inclusion criteria. Patients with acne vulgaris have a significantly higher level of anxiety, depression, and stress (P<0.05). Yet, the reported findings of the SCL-90-R, self-esteem, loneliness, and BDNF scores among patients suffering from acne vulgaris were variable and did not differ significantly compared to healthy participants (P>0.05), hampering any conclusive findings on absolute prevalence. Subgroup analysis and comparison showed that heterogeneity between studies was likely due to factors, including country, study design, and assessment tools. This comprehensive review and meta-analysis revealed that anxiety, depression, and stress are significantly more frequent among patients suffering from acne vulgaris. These findings confirm that acne vulgaris has both psychiatric and medical characteristics and requires a multidisciplinary approach.

Infertility is often associated with diverse psychiatric morbidities and quality of life impairments. Hence, this meta-analysis aimed to compare stress, depression, anxiety and quality of life (QoL) among infertile men and women. We retrieved the relevant articles from multiple databases. For the statistical analyses, we used Comprehensive Meta-Analysis software v. 3.7 (Biostat Inc., Englewood, NJ). Standardized mean differences (SMD) with 95% confidence intervals (CI) were calculated and displayed in forest plots. Among the 4123 articles identified, 35 studies met the inclusion criteria. Our results revealed that stress, depression, and anxiety were higher in infertile women compared to men. Similarly, infertile women presented a lower QoL than infertile men. Subgroup analysis revealed that the assessment tool used, study design, and geographical origin were a source of heterogeneity. This meta-analysis showed that psychological disturbances were higher in infertile women compared to men. Physicians need to consider this difference to enable couples to better understand and support each other.

Purpose The term muscle dysmorphia (MD) refers to the pathological desire to increase lean muscle mass coupled with a persistent belief that one is not muscular enough. The disorder was recently classified under the umbrella of obsessive-compulsive disorder in DSM-5. The individuals social view and sense of self-worth are impacted by MD. Consequently, functional impairment occurs. The assessment of MD is made with the muscle dysmorphia Disorder Inventory (MDDI). The purpose of the study is to validate the Arabic version of the MDDI ensuring the availability of the instrument in Arabic-speaking nations. Methods 1118 participants (58% female, average age 28 years) participated in the translation of MDDI through an internet-based survey. Results Based on multigroup confirmatory factor analysis (CFA), the three-factor structure of the English MDDI was replicated, independent of gender (TLI = 0.85, CFI = 0.90, RMSEA = 0.09). The reliability was evaluated via Cronbach's α and McDonald's ω for the total MDDI scale and the sub-scales. Cronbach´s alpha was 0.71 for DFS, 0.71 for AI and 0.82 for FI, and 0.70 for the MDDI total score. Men and women showed differences in three subscales of the MDDI (DFS, AI, FI). McDonald's Omega showed an Al of (0 .72) DFS (0.72) FI (0.83) and total MDDI (0.82). Conclusion The MDDI-13 Arabic translation proved to be valid. Thus, the results are consistent with using the measure in Arabic-speaking nations. Level of evidence: Level V descriptive cross-sectional study.