Nomophobia is an emerging phenomenon in the 21st century. Consequently, it results in various health problems, both physical and psychological. The following systematic review and meta-analysis aimed to establish the relationship between nomophobia with anxiety, smartphone addiction, and insomnia. To identify the relevant studies, we searched through several databases. Out of the 1523 studies identified, 16 studies met the inclusion criteria. After conducting the statistical analysis, the results revealed that anxiety r = 0.31 (95% CI: 0.25 to 0.38), smartphone addiction r = 0.39 (95% CI: 0.04 to 0.75), and insomnia r = 0.56 (95% CI: 0.38 to 0.75) are positively associated with nomophobia. Mobile phone usage has become inevitable, even for individuals who use it to a lesser degree than others, to perform simple tasks, such as communicating with others or for educational purposes. It is crucial to raise awareness about the consequences of overusing these devices, including the physical and psychological complications in both the short and long terms.

Smegma pearls, also called smegmomas, are a natural secretion composed of epithelial cells, protein, and fat. Smegma pearls are not carcinogenic and do not induce damage or irritation. Despite the frequent occurrence of smegma pearls in uncircumcised children, no case among circumcised patients was reported. Here, we are presenting, for the first time, a case of smegma pearl in a circumcised patient. A 36-year-old circumcised male patient presented with a smegma pearl. The purpose of the present case report is to describe the diagnosis of this benign condition in circumcised patients, yet not described in the literature, and help physicians to enhance patient management and avoid needless investigations or treatments.

Acne vulgaris usually affects the dermal layer of the skin and is revealed frequently in young adulthood and adolescence. It has serious psychosocial comorbidities. We conducted the present systematic review and meta-analysis to elucidate the association of acne vulgaris with psychiatric comorbidities and quality of life as well as the brain-derived neurotrophic factor (BDNF) level. A systematic review and meta-analysis of the published articles were carried out following the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. We investigated diverse databases: Web of Science, PubMed, the Cochrane Library, Embase, PsycINFO, and CINAHL to search for articles reporting the prevalence of psychosocial comorbidities among patients with acne vulgaris from database inception through June 2022. The outcomes were depression, anxiety, symptom checklist-90-R (SCL-90-R), quality of life, self-esteem, stress, loneliness, and BDNF concentrations. Of 3647 articles identified, 23 met the inclusion criteria. Patients with acne vulgaris have a significantly higher level of anxiety, depression, and stress (P<0.05). Yet, the reported findings of the SCL-90-R, self-esteem, loneliness, and BDNF scores among patients suffering from acne vulgaris were variable and did not differ significantly compared to healthy participants (P>0.05), hampering any conclusive findings on absolute prevalence. Subgroup analysis and comparison showed that heterogeneity between studies was likely due to factors, including country, study design, and assessment tools. This comprehensive review and meta-analysis revealed that anxiety, depression, and stress are significantly more frequent among patients suffering from acne vulgaris. These findings confirm that acne vulgaris has both psychiatric and medical characteristics and requires a multidisciplinary approach.

Palisaded neutrophilic and granulomatous dermatitis (PNGD) is a rare reaction pattern that is frequently linked to several systemic diseases, including autoimmune disease, inflammatory bowel disease, and vasculitis. Churg-Strauss syndrome (CSS) is an uncommon systemic condition that occurs exclusively in patients with asthma or a history of atopy. It is characterized by extravascular necrotizing granuloma and hypereosinophilia. This case report describes an illustrative case of a 61-year-old Bahraini female who had been diagnosed with CSS and presented with PNGD. The PNGD appeared a few weeks after her oral corticosteroid medication was discontinued. The present case report aims to assist in accurately diagnosing PNGD, as rarely manifested in this case, thus aiding clinicians in improving patient care.

Infertility is often associated with diverse psychiatric morbidities and quality of life impairments. Hence, this meta-analysis aimed to compare stress, depression, anxiety and quality of life (QoL) among infertile men and women. We retrieved the relevant articles from multiple databases. For the statistical analyses, we used Comprehensive Meta-Analysis software v. 3.7 (Biostat Inc., Englewood, NJ). Standardized mean differences (SMD) with 95% confidence intervals (CI) were calculated and displayed in forest plots. Among the 4123 articles identified, 35 studies met the inclusion criteria. Our results revealed that stress, depression, and anxiety were higher in infertile women compared to men. Similarly, infertile women presented a lower QoL than infertile men. Subgroup analysis revealed that the assessment tool used, study design, and geographical origin were a source of heterogeneity. This meta-analysis showed that psychological disturbances were higher in infertile women compared to men. Physicians need to consider this difference to enable couples to better understand and support each other.