Chronic Myeloid Leukaemia is very uncommon in children. It accounts for 2 to 5% of all the childhood leukaemias. The incidence is < 1 case per 1,00,000 population in younger than 20 years of age per year. Two distinct forms have been described- namely the Juvenile and Adult type. Absence of Philadelphia chromosome is the hallmark of Juvenile type CML ( JCML). Adult type CML is extremely rare in childhood. Here, we report one such a case of adult type of CML in an 11 year old girl who presented to us with pallor, fever and hepato-splenomegaly. At presentation, it seems to be a case of Visceral Leishmaniasis. But, peripheral blood film and bone marrow features were consistent with CML. Philadelphia chromosome was positive. Though biological behavior and prognosis are identical to that of adult CML, we are reporting this case because of its extremely uncommon incidence.Bangladesh J Medicine Jul 2014; 25 (2) : 72-75
Named after Sir Alfred Poland, Poland syndrome is a rare congenital anomaly classically characterized by the absence of unilateral chest wall muscles and sometimes ipsilateral symbrachydactyly (abnormally short and webbed fingers). The aetiology is probably a vascular disruption sequence of the subclavian arteries. In most cases, Poland Syndrome is sporadic. We report a 26 year old male patient with typical features of Poland Syndrome associated with bronchiectasis and mitral valve prolapse- a very rare association. To the best of our knowledge, this is the first documented case of a Poland Syndrome with rare association reported from Bangladesh.J Bangladesh Coll Phys Surg 2018; 36(4): 166-169
Tuberculosis is very common in our country. It can involve many organs and have broad spectrum of image presentation. It may resemble malignant diseases, especially in the elderly and thus confuse the judgement of the clinician. We report a case of a 58 year old gentleman presenting with chronic cough, low grade fever, weight loss for 16 months; features of progressive marrow failure for 8 months and severe low back pain without any neurological features for 2 months. The CT scan of spine revealed lytic lesions of vertebrae sparing the intervertebral discs, thus resembling metastatic lesions of bone. We approached this case as malignant disease initially, but found it to be a disseminated tuberculosis infection involving lungs, bone marrow and spine after a series of investigations. Though disseminated TB is not uncommon in our country, the purpose of presenting this case is to give emphasis that, clinicians should consider Potts disease (spinal tuberculosis) in the differential diagnosis of patients with back pain and destructive vertebral lesions. Proper diagnosis and anti-tuberculous treatment with or without surgery will result in cure of the patientBangladesh J Medicine Jul 2016; 27(2) : 81-85
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