Purpose To compare the biomechanical and histological properties of Achilles tendons repaired at different time points during the acute injury period. Methods Thirty‐six skeletally mature Sprague–Dawley rats underwent bilateral mid‐substance Achilles tenotomy. The Achilles tendons were repaired either in the first 24 h (group 1), 24–48 h (group 2), 48–72 h (group 3), or > 72 h (mean: 120 ± 5.2 h) (group 4) after tenotomy. Six weeks after repair, nine tendons per group were assessed biomechanically and histologically. The Stoll histological scoring system was used for histological examination. The groups were compared with each other and native tendons (control group). The correlations between biomechanical and histological results were analysed. Results There were no significant differences between groups 1, 2 and 3 regarding the mean load to failure; it was significantly lower in group 4. Healed tendons in groups 1, 2 and 3 had significantly greater stiffness than native tendons and group 4 tendons. All healed tendons had a larger cross‐sectional area than native tendons. There was no significant difference in tendon length between the groups. There was no significant difference in Young's modulus between the groups; Young's modulus was lower in all the groups than in the control group. Group 1 had significantly higher extracellular matrix organization, cell alignment, cell distribution and nucleus morphology scores and total scores than group 4. Group 1 had significantly higher extracellular matrix organization, cell distribution, vascularization and inflammation scores and total scores than group 3. A significant positive correlation was detected between the maximum load to failure and total histological score. Conclusion Repair of acute Achilles tendon rupture within 48 h, and especially in the first 24 h, provides better biomechanical and histological outcomes. In the clinical practice, the data could be used to decrease re‐rupture rates, to achieve more anatomical tendon healing and to implement more effective post‐operative rehabilitation programme.

Besides the applications aimed at increasing the efficiency of the Android mobile devices, also many malicious applications, millions of Android malware according to various security company reports, are being developed and uploaded into the application stores. In order to detect those applications, a malicious Android application detection system based on permission and permission groups namely, AppPerm Analyzer has been developed. The AppPerm Analyzer software extracts the manifest and code permissions of analyzed applications, creates duple and triple permission groups from them, calculates risk scores of these permissions and permission groups according to their usage rates in malicious and benign applications and calculates the total risk score of the analyzed application. After training the software with 7776 applications in total, it is tested with 1664 benign and 1664 malicious applications. In the tests, AppPerm Analyzer detected malicious applications with an accuracy of 96.19% at most. At this point, sensitivity (true-positive ratio) is 95.50% and specificity (true-negative ratio) is 96.88%. If a false-positive ratio up to 10% is accepted, the sensitivity increases to 99.04%.

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