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Introduction: To evaluate the variables affecting prognostic factors in patients with salivary gland cancer who have received surgery followed by radiotherapy. Methods: Fifty-three patients with major and minor salivary gland cancer who treated with curative surgery and postoperative radiotherapy between 1993 to 2011. We evaluated with regard to overall survival, locoregional recurrence-free survival, disease free survival, distant metastases free survival. Results: The median follow-up period was 40 (8-174) months. The rates of local control, distant metastasis-free, disease free survival and overall survival after 10 years were 65%, 57,7%, 38,8%, and 48,2%, respectively. In univariate analysis, histological subtype, histologic grade, extraglandular extension and delivered dose of RT were found to be as prognostic factors affecting on locoregional recurrence-free survival; gender, histological subtype, extraglandular extension influenced disease-free survival; overall survival was only affected by age. In multivariate analysis, locoregional recurrence-free survival was affected by histologic grade, and dose of RT(60 Gy< better prognosis); distant metastasis-free survival was affected by histological subtype; disease-free survival was affected by histological subtype, histologic grade, lymph node status; overall survival was affected by lymph node status, extraglandular extension and dose of RT (60 Gy< better prognosis). Conclusion: Several prognostic factors affecting local control, distant metastases, and overall survival were found. Postoperative radiotherapy is an affective treatment modality that increases local control and overall survival in patients with Salivary Gland Carcinoma at doses over 60 Gy.

Background. Nasopharyngeal carcinoma (NPC) is one of the rare malignant diseases of childhood, of which only 1% occurs in children. In recent years, genetic factors have attracted attention in NPC. A very limited data have been reported about clustering within families. Case. Herein, the familial clustering of nasopharyngeal carcinoma in the family of an adolescent with nasopharyngeal carcinoma is presented. Conclusions. There is familial clustering in nasopharyngeal carcinoma (NPC), but our knowledge on this subject is limited, especially in children or adolescent populations. Therefore, we should be more careful in NPC in childhood, especially in first-degree relatives.

Objective: This study aimed to determine the knowledge, attitudes and behaviors of students in a medical school regarding breast self-exam and also to explore their level of knowledge regarding breast cancer. Methods: The research was carried out in Selcuk University Faculty of Medicine in April 2022, among medical students. The universe of the study consisted of all medical school students and it was conducted with 221 volunteers who accepted the study. Participants were asked questions about breast cancer and breast self-exam. Results: Two-hundred twenty one students participated in the study. The mean age was 20,71±2,108 (range 18-32). Of the 221 participants, 67% (n: 148) were female and 33% (n: 73) were male, and 76.5% (n: 169) were preclinical (1st-2nd-3rd year) students, and 23.5% (n = 52) were clinical (4th-5th-6th year) students. 69.2% of the participants reported that they had knowledge about breast cancer. 66.8% (n:147) of the students stated that they did not perform BSE, when it was questioned why those who did not perform it, 68.8% (n:93) of them did not have enough information. Conclusion: As a result of the survey in which the knowledge, attitude and behavior of medical school students about breast cancer and BSE were evaluated, it was concluded that there is a lack of knowledge about breast cancer. Regarding BSE, it was also determined that the students were not sufficient for both self-application and knowledge. Especially for developing countries, it is a cost-effective and effective screening method for use that can be useful in the early diagnosis of breast cancer when done correctly.