Introduction: To evaluate the variables affecting prognostic factors in patients with salivary gland cancer who have received surgery followed by radiotherapy. Methods: Fifty-three patients with major and minor salivary gland cancer who treated with curative surgery and postoperative radiotherapy between 1993 to 2011. We evaluated with regard to overall survival, locoregional recurrence-free survival, disease free survival, distant metastases free survival. Results: The median follow-up period was 40 (8-174) months. The rates of local control, distant metastasis-free, disease free survival and overall survival after 10 years were 65%, 57,7%, 38,8%, and 48,2%, respectively. In univariate analysis, histological subtype, histologic grade, extraglandular extension and delivered dose of RT were found to be as prognostic factors affecting on locoregional recurrence-free survival; gender, histological subtype, extraglandular extension influenced disease-free survival; overall survival was only affected by age. In multivariate analysis, locoregional recurrence-free survival was affected by histologic grade, and dose of RT(60 Gy< better prognosis); distant metastasis-free survival was affected by histological subtype; disease-free survival was affected by histological subtype, histologic grade, lymph node status; overall survival was affected by lymph node status, extraglandular extension and dose of RT (60 Gy< better prognosis). Conclusion: Several prognostic factors affecting local control, distant metastases, and overall survival were found. Postoperative radiotherapy is an affective treatment modality that increases local control and overall survival in patients with Salivary Gland Carcinoma at doses over 60 Gy.