Some aspects and technologies of knowledge delivery during the COVID-19 pandemic and the full-scale military invasion of Ukraine by the Russian Federation, which led to the occupation of certain regions and the destruction of many educational institutions in the areas of active hostilities, are considered. Many children who left the territory of Ukraine with their parents have significant problems with online education. University applicants who stay in the temporarily occupied territories are forced to avoid the enemy’s common practice to Russify the educational process and impose their methodological narratives. Part of the teaching staff ceased their professional activities in domestic higher education institutions. Such difficulties in the educational process in Ukraine are related, in particular, to the inadequate access of potential users to the online environment, to the problems that have arisen in the activities of higher education institutions. In view of this, directions to address those issues in the process of educational activities digitalization are proposed, the dynamics of Ukraine population’s access to electronic and digital resources is analyzed, and a model of knowledge delivery to pupils and students during the pandemic and war is developed. The future requirements for education in the process of digitalization are detailed, and the challenges that the higher education institutions will face in the future are structured. The directions of development and application of artificial intelligence technologies in the educational sphere are substantiated. A three-component flowchart of the "road map" for progressive actions aimed at the implementation of artificial intelligence in the system of staff training by higher education institutions is proposed. The need for institutional improvement of higher education institutions activities, modernization of their technological resources is proved, the vectors of artificial intelligence development are proposed. The areas of neurotechnologies application and the ethical limits of their use are defined. The need to synchronize the actions of higher education institutions, stakeholders and users to achieve a synergistic effect of digitalization and the implementation of artificial intelligence in educational activities has been emphasized.