Pilocytic astrocytoma is a benign low-grade tumor with a favorable prognosis. We present a 47-year-old- lady with a posterior fossa pilocytic astrocytoma who underwent surgical decompression. She developed multiple early local recurrences Along with malignant transformation of the cranial lesion she developed skeletal dissemination within a very short time frame. There were no features or family history of neurofibromatosis 1. She did not receive radiotherapy or chemotherapy prior to the recurrences.
OBJECTIVES:To establish the validity and reliability of imprint cytology and its accuracy in intra operative diagnosis of ovarian tumours and to compare it with the histopathology reports. METHODS: Multiple imprints were taken from 30 surgical specimens of patients suspected of ovarian neoplasms who underwent surgery as primary line therapy at our institution. This was compared with Final pathological diagnoses. We calculated the limits among benign, borderline, and malignant lesions, and analyzed the diagnostic accuracy. RESULTS: 30 cases were studied during this study period from November 2011 to October 2013. 19 (63.3%) cases were benign, 8 cases were malignant (26.7%), 1 (3.3%) case was borderline malignancy and 2 (6.7%) cases were excluded. Overall diagnostic accuracy was 96.4%. CONCLUSION: Imprint cytology is a less expensive, simple and quick method of diagnosis, and is reliable in terms of accuracy to aid decision making intraoperatively.
Background: In acute coronary syndrome, prompt restoration of myocardial blood flow is essential to optimize myocardial salvage and decrease mortality. Coronary artery reperfusion, if performed in a timely manner improves clinical outcomes compared to no reperfusion. Fibrinolysis and percutaneous interventions can restore blood flow in an acutely occluded coronary artery in most of the patients; but in a few subset of patients coronary artery bypass grafting (CABG) is needed to effectively restore blood flow.Methods: A retrospective study was conducted among all CABGs performed during March 2016 - February 2018. During this period, 366 CABGs were performed and 57 patients underwent emergency CABG as per the inclusion criterias. Pre-operative, intra-operative and post-operative data was analysed of these patients. Patients were divided into four groups based on the time of surgery from the time of onset of myocardial infarction. Results: 57 patients underwent emergency CABG with males constituting 94.7% of the study population. 78.9% of them had an ejection fraction less than 35%. 52% presented with low cardiac output status, 10% needed intra-aortic balloon pump support and 15% required mechanical ventilation prior to surgery. All patients received an average of 2.8 grafts. Mortality was 5%Conclusions: Immediate surgical revascularisation of patients presenting with acute MI is feasible. Emergency CABG not only treats the culprit lesion but also achieves complete revascularization and offers a clear advantage for patients. The optimal timing of CABG for patients with acute MI remains difficult to establish.
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