No abstract

The surge of Dengue cases around the globe has intensified the demand for a reliable diagnostic method. The work demonstrates, to the best of our knowledge, the first label-free optical based sensor for detection of Dengue II E proteins. This was achieved by utilizing tapered optical fiber that has been functionalized with complementary recombinant antibodies. The fundamental concept of the sensor relies on the interaction between strong evanescent waves resulting from the dimensional change of the fiber and immune complex formed on the surface of the fiber when the virus is present. Sensitivity and detection limit values obtained with the sensor setup are 5.02 nm/nM and 1 pM, respectively, with a standard deviation value of no more than ±0.4. The compact and rapid sensor is a viable alternative for label-free and quantitative assessment of the infection, which may assist in providing better clinical management and understanding of the disease.

Low-dimensional materials as saturable absorbers (SA) for pulsed laser applications have gain wide interest due to high nonlinearity and strong light-matter interaction. Various materials have been investigated such as graphene, transition metal oxides (TMO), transition metal dichalcogenides, and topological insulators. Tungsten trioxide (WO3); a cheap and nontoxic type of TMO has not yet been investigated for mode-locked pulsed fiber laser (MLFL) generation despite extensive employment as applications in other fields. WO3 is very attractive with spectral absorption extending in the broad near infra-red region, good mechanical strength, high resistance to photo corrosion, and is one of the few oxides that has high thermal and chemical stability. A tungsten trioxide (WO3) based saturable absorber (SA) fabricated via deposition of WO3 composite on tapered fiber was demonstrated. The WO3 weight percentage was varied from 0.005 to 1.235 wt% to investigate the effect on nonlinear saturable parameters and on mode-locked lasing performance. It was determined that the nonlinear saturable parameters were not dependent on weight percentage within its working range; 0.025 to 1.103 wt%. The generation self-started with 35-70 mW pump power, where the pulse durations and spectral bandwidths fall within the range of 810-940 fs and 8-12 nm, respectively. This experimental investigation provides insight on WO3 as a saturable absorber for mode-locked pulse laser generation. The utilization of this nanomaterial is aimed to cut down the cost the existing SA technology while providing enhanced durability and shelf-life.

We experimentally demonstrate a passively Q-switched erbium-doped fiber laser incorporating microfiber-based titanium dioxide (TiO2) polymer composite saturable absorber. The anatase TiO2 is derived from natural ilmenite waste via alkaline fusion method. The TiO2 polymer composite is prepared using solvent exchange method and deposited onto tapered microfiber via dip coating technique. The passive Q-switching at 1558.3 nm with low threshold pump power of 16.4 mW, average output power of 1.0 mW and pulse energy of 47.6 nJ are realized. The shortest pulse width of 7 μs with 22.56 kHz repetition rate is recorded. This work opens up a new window for the generation of microsecond pulses using waste material.

No abstract