According to WHO data about 60-80 million people around the world suffer from infertility. This problem causes huge negative impact on family life. Forty percent of women with infertility experience various mental disorders. Aims/objectives: Investigation of anxiety-depressive spectrum disorders in women with infertility. Assessment of impact of women infertility on self-esteem and certain aspects of life. Development of recommendations on mental health services for women, experiencing infertility problems. Methods: Sixty women at the age of 21 to 36 years, experiencing infertility problems for maximum period of 60 months participated in the study. Anxiety, depression and stress rates were assessed using Depression, Anxiety and Stress Scale-DASS-21, the level of self-esteem was determined with Rosenberg Self-Esteem Scale. Data was analyzed using SPSS 16.0. Results: Such factors as education, occupation, religious beliefs, and accessibility of proper medical services were determined to have significant impact on depression, anxiety and stress rates as well as on self-esteem and satisfaction with life of women with infertility. Conclusions: Screening for early detection of mental health problems, psychological counseling and family therapy for couples encountering infertility problems was recommended.

Mövcud tədqiqatın məqsədi, doğuşdan sonrakı ilk günlərdən bəri mukozal bağırsaq ifrazı vəziyyətinin qiymətləndirilməsinə əsasən atopik dermatit meydana gəlməsinin proqnozlaşdırılmasıdır. Yenidoğulmuş dövrdə, doğumdan 1-3 gün sonra immun ferment analizləri üsulu ilə alınmış oksigenli qan serumundakı rutin analizlərlə birlikdə MUC-2 və ITF səviyyələrini təyin edirik ki, bu da bağırsaq ifrazının baryer vəziyyətini əks etdirir. 37-42 həftədə hamiləlik yaşı olan 414 tam müddətli yeni doğulmuş körpələr müayinə edildi. Həyatın ilk günlərindən bəri MUC-2-nin yüksək konsentrasiyasına məruz qalan qədəh hüceyrələrinin hiper sekresiyası ontogenezin sonrakı mərhələlərində atopik dermatitin əmələ gəlməsində perinatal risk faktorlarının təsiri altında bağırsaq mukozal baryerinin pozulmasına imkan verir. Atopik dermatitdə ITF məlumatları ilə müqayisədə MUC-2 səviyyəsinin aşkar dəyişiklikləri antenatal dövrdə pozuntu şəfqəti altında bağırsaq baryerindəki birinci komponentin daha böyük həssaslığını göstərir. Bu MUC-2 məlumatları atopik mülkiyyətdə olan uşaqlarda proqnozlaşdırılan atopik dermatit inkişafının biomarkerləri kimi qəbul edilməlidir.

Background: Early forecasting of any pathological process is of great significance from both medical and economic point of view. An illness requires much more attention in the light of exhaustion of resources of the body, and a doctor should be maximally aware of the near and far future of a patient. In this regard, the preparation of forecasting programs on a mathematical basis would be a rational and, most probably, the only true approach to the solution of forecasting. Aims and Objectives: The aim of the article is to study the forecasting of atopic dermatitis (AD) in newborns. Methodology: The authors studied 109 clinical and laboratory indicators in children without and with AD. Discriminant analysis was used as an algorithm for the resolution of diagnostic issues. Results: The main indicators acceptable as a forecasting criterion in the formation of AD in children were defined. The sensitivity, specificity, and general diagnostic value of statistically valid differing factors in the formation of AD were studied. Key rules of the forecast were formed after processing all indicators through the KU–Kruskal–Wallis discriminant criterion, a universal computer method. Conclusion: It was concluded that the power of influence of rhinitis, cluster of differentiation 31, mucin 2, and intestinal trefoil factor 3 are higher in the AD model.