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199 ChemInform Abstract Reaction of allyl isothiocyanate (I) with ethylenediamine (II) gives the bisthiourea (III) which is cyclized on heating, producing the bisthiazoline (IV). Bromination of (III) and subsequent cyclization yield the bromomethyl derivative (V), treatment with ethyl iodide (VI) forms the isothiuronium salt (VII). The compounds (VIII) -(XII) are synthesized in the same manner. Coupling of the glycine ester (XIII) with (I) in the presence of sodium ethylate leads to the formation of the imidazole derivative (XIV). The compound (XV) is obtained from (XIII), (I), and (II). The compounds synthesized have no radioprotective activity.

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