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Background: Diabetes is a chronic, progressive disease characterized by elevated levels of blood glucose and is recognized as an important cause of premature mortality and morbidity. Self-care practice in diabetes patient is a critical factor to achieve glycaemic control thus in preventing or delaying its complications.Methods: A cross sectional study was conducted among 140 type 2 diabetic patients attending the outpatient department in Karnataka Institute of Medical Sciences, Hubballi during the period of June-July 2018. Diabetic patients diagnosed more than 3 months were included. Data was collected by interview method using pre-designed, pre-tested and semi-structured questionnaire which consists of information on socio-demographic data, diabetic profile, self-care practices and dietary barriers. Statistical analysis was done using SSPS package.Results: This study showed that 67.9% of study participants were consuming diabetic diet, 17.1% practice exercise for more than 3 days a week, 93.6% were taking medication regularly, 15% practised foot care for >3times a week and 89.3% monitored their blood glucose regularly. The main barriers for dietary practices were lack of knowledge (24%) and lack of motivation (18%). Compliance to diabetic diet was more among the urban population compared to rural (p=0.025).Conclusions: Study concludes that the practice of self-care activities was poor in almost all aspects except for blood sugar monitoring and adherence to medication which necessitates the need to create awareness regarding self-care practices and its importance among diabetic patients.

Aim:The present study was carried out to know the expression level of survivin, an inhibitor of apoptosis protein with an objective to determine its prognostic importance in cutaneous and subcutaneous tissue tumors of dogs.Materials and Methods:Forty cases of canine cutaneous and subcutaneous tissue tumors on histopathological examination revealed various round cell, epithelial, and mesenchymal cell tumors. Survivin gene expression was detected in all tumors tested by TaqMan real-time polymerase chain reaction assay by comparative cycle threshold method.Results:The mean survivin gene expression value of benign tumors was 0.94±0.63 folds and that of malignant tumors was 18.87±5.30 folds. Postsurgical follow up of 30 malignant tumor cases revealed death in 8, recurrence in 7, and neoplastic free alive status in 15 dogs with mean survivin fold difference values of 48.49±12.39, 14.63±6.37, and 5.034±2.27, respectively. The mean survivin gene expression value was significantly higher in malignant (30 cases, 18.87±5.30) compared to benign tumors (10 cases, 0.94±0.63), and it varied between various postsurgical follow-up groups (p<0.05). Survival analysis, using survivin gene expression median cutoff value of 3.74 in 30 malignant tumors, was performed to predict probable survival period in malignant cutaneous and subcutaneous tumors of dogs.Conclusions:Results of the present study indicated that the expression of survivin in canine cutaneous and subcutaneous tumors has prognostic value, and survivin expression greater than median cutoff value of 3.74 has a poor prognosis.

Breast cancer is the most common cancer among women in the world today. Mammography screening gives vital information about normal and abnormal regions. The task is to detect the lesion in mammograms using computer-aided diagnosis techniques. The automated detection of cancer decreases the mortality rate and manual error. In this work, the statistical (mean, variance, skewness, kurtosis, energy and entropy) and tamura features (coarseness, contrast and directionality) were extracted from the Cranial-Caudal (CC) view of mammogram images collected from the M.S. Ramaiah Memorial Hospital, Bangalore. The support vector machine was used for classification. Different support vector machine kernels were used and results were tabulated. The highest accuracy was obtained for linear and quadratic kernels with 95.7% with sensitivity of 100% and specificity of 91%.