Isobutyl cyanoacrylate tissue adhesive (BCTA) was used in the treatment of refractory superficial corneal ulcers in 17 dogs, one cat, and one rabbit, present 2 weeks to 7 months (mean 6.8 weeks +/- 6.1) prior to referral. Little to no sedation was required in the majority of cases, with only topical anesthetic applied prior to debridement and BCTA application. The presence of the tissue adhesive caused mild discomfort for several days after application, as reported by the owners. The ulcers healed, and the tissue adhesive sloughed in approximately 3 weeks (+/- 1 week). Mild neovascularization of the cornea resolved with topical corticosteroids. The use of BCTA offers a simple, safe and noninvasive treatment for refractory corneal ulcers.
The visual acuities (i.e., visual thresholds for pattern detection) of four dogs under neuromuscular block were measured using visually evoked cortical potentials (VECP) and/or pattern-evoked retinal potentials (PERR). Stimuli were phase-reversing square-wave gratings with a mean luminance of 86 cd/m2 and 70% contrast. The mean of the VECP thresholds of two dogs tested was 12.59 cycles per degree (cycles/deg). The mean of the PERR thresholds of four dogs tested was 11.61 cycles/deg. The difference between VECP and PERR thresholds was not statistically significant. VECP acuities appear to be determined at or before the last stage of retinal processing (PERR). Our estimates of canine acuity are 1.3-2 times those reported for cats and 0.2-0.4 times those reported for primates when tested under comparable luminance and contrast conditions.
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