Background and Objectives: Inflammatory processes play an important role in intra-articular fractures. The present study aimed to examine the relationship between chemerin, high-sensitivity C-reactive protein (hs-CRP), and Interleukin 17 (IL-17) serum and synovial fluid levels of osteoarthritis patients and individuals with intra-articular fractures. Method:In this case-control study, all osteoarthritis patients and individuals with intra-articular fractures who visited the Imam Khomeini Orthopedic Clinic of Ahvaz were examined. Blood samples (5 cc) were collected prior to surgery to measure chemerin Interleukin 17, and hs-CRP serum levels. Synovial fluid samples (2 cc) were collected during the surgery. Results:Measuring the levels of IL-17, chemerin and hs-CRP indicated a significant statistical difference between the serum and synovial fluids of osteoarthritis patients, individuals with intra-articular fractures, and the control group (p < .001). Post-hoc analyses showed statistically significant differences in all conditions except for hs-CRP levels between osteoarthritis patients and individuals with intra-articular fractures.Conclusion: Discovering ways to stop or slow down osteoarthritis is a matter of great concern. The findings on osteoarthritis indicate diverse, complex, and multidimensional processes involving cytokines. Information on cytokines that effect diseases can help develop efficient therapy methods.

An attempt was taken to compare the results of treatment of intertrochanteric fractures using Dynamic Hip Screw (DHS) and gamma-nail by a retrospective cross-sectional study on 108 male and female patients as participants aged 40 to 80 years suffering from stable and unstable intertrochanteric fractures. Participants underwent surgery in one of the two methods: DHS (n = 61) or gammanail (n = 47) and clinical evaluation in the last follow-up session, including union, lameness, and limb length discrepancy (LLD) under the supervision of an orthopedic surgeon. The Harris Hip Score (HHS) questionnaire was f illed up by the patients to evaluate and compare functional recovery. Including demographic questionnaires, associated injuries (such as infection, lameness, and pain) were also tabulated. Post-surgical complications including surgical failure, deep infection, and LLD were also investigated. Ultimately, patients' ambulation status and walking status with or without auxiliary devices were evaluated. Results evidenced the higher surgery failure in the gamma-nail group (10.44%) than in the DHS group (4.59%). The LLD was less than 2 cm in both groups and was not symptomatic. Non-union rate and deep infection in the gamma-nail group were statistically higher. The mean of bleeding during surgery and duration of surgery in the gamma-nail group was also signif icantly lower.