Objective: The purpose of this research is to assess the antioxidant activity of lemongrass leaves extract in terms of lowering ROS generation and its effect on the viability and proliferation of fibroblasts under oxidative stress. Material and Methods: The antioxidant activity was measured using the DPPH method and the ROS assay was carried out by fluorescent H2DCFDA staining. Viability and proliferation assays were performed using the Cell Counting Kit-8 (CCK-8) and was read at 450 nm using microplate reader. The groups were divided into 8, namely fibroblasts without treatment (comparison group), fibroblast induced by H 2 O 2 (negative control), fibroblast with H 2 O 2 then treated with ascorbic acid (positive control), and fibroblast with H 2 O 2 then treated with lemongrass leaves extract at various concentrations (10, 20, 30, 40, and 50 ppm). Results: The results showed that the antioxidant activity of lemongrass leaves extract had an IC 50 value of 64.17 ppm. ROS production were reduced by the LgLE of all concentrations if compared with negative control (p=0.819). LgLE can maintained the fibroblast viability with 10 ppm of LgLE was the most optimum concentration (p<0.05). LgLE can induced the proliferation of fibroblast, with the most effective was at 24 h of observation (p<0.05). Conclusion: Lemongrass leaves extract has a strong antioxidant activity that can reduce oxidative stress and increase the viability and proliferation of fibroblasts with the optimum concentration is at 10 ppm.

Penelitian ini bertujuan untuk mengetahui apakah terdapat pengaruh kesadaran merek dan kualitas produk terhadap kepuasan konsumen pada toko busana muslim Venka Gallery Banda Aceh. Penelitian ini merupakan penelitian kuantitatif, dimana sampel yang diambil sebanyak 100 responden yaitu seluruh konsumen toko Venka Gallery Banda Aceh dengan menggunakan teknik purposive sampling. Jenis data yang digunakan adalah data primer yaitu mengedarkan kuesioner melalui google form. Metode analisis penelitian dilakukan dengan menggunakan regresi linear berganda. Penelitian menemukan bahwa kesadaran merek dan kualitas produk secara simultan dan parsiall berpengaruh positif dan signifikan terhadap kepuasan konsumen. Berdasarkan uji R2 pengaruh yang diberikan oleh variabel independen terhadap variabel dependen sebesar 36,0 % sedangkan sisanya 64,0 % dipengaruhi oleh variabel lain yang tidak disertakan dalam penelitian ini.