Background: There is a tight association between preeclampsia and infection with H. pylori explained by in vitro studies. Objective: To evaluate the relationship between maternal infection with Helicobacter pylori and the occurrence of preeclampsia (PE) and the perinatal outcome. Subjects and Methods: Ninety-two pregnant women were included in this comparative observational study. Serum Immunoassay for H. Pylori IgG seropositivity was done for all patients. Results: The preeclamptic group shows statistically significant higher values of liver transaminase enzymes, total Bilirubin and decreased S. alb. These findings donate that liver is significantly affected in preeclampsia. There is statistically significant association between maternal infection with H. pylori and the increased incidence of intrauterine fetal death (IUFD), the need for neonatal intensive care unit (NICU) admission. And also, increased severity of preeclampsia and the occurrence of hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome. But the association with eclampsia was insignificant. Conclusion:There is association between PE and infection with H. pylori as H. pylori sero-positivity is higher among women with preeclampsia and increased perinatal feto-maternal complications among patient with H. pylori infection.

Background: Preoperative diagnosis of adenomyosis and uterine myoma can be aided by pelvic ultrasonography and cancer antigen 125 (CA125). Objective: This study aimed to evaluate the usefulness of CA125 level and transvaginal ultrasonography in diagnosis of uterine myoma and adenomyosis and to differentiate both lesion. Patients and Methods: One hundred patients complaining of abnormal uterine bleeding were included in this study. They were attending the Obstetrics and Gynecology Departments at Zagazig University Hospitals and Al-Ahrar Teaching Hospital for hysterectomy. Transvaginal ultrasonography (TVS) was done for all selected cases to examine the pelvis for detecting any pathology. CA 125 level was measured. Hysterectomy specimens were histopathologically examined. Results: The combination of serum CA125 level and TVS showed that it was useful in adenomyosis group as CA125 level increased the accuracy of TVS from 77% to 80.2%, while in myoma group the combination was not useful as CA 125 decreased the accuracy of TVS from 100% to 83.3%. Conclusion: Transvaginal ultrasonography is the most sensitive for myoma (100%) & CA125 level is the most specific (77%) for adenomyosis. CA125 level had the highest sensitivity (87.5%) for adenomyosis than transvaginal ultrasonography (80.1%). Combining both TVS and CA125 level increased the accuracy for detection of adenomyosis to 80.2% but decreased it to 83.3% in detection of uterine myoma.

Background: In patients who have already undergone a cesarean section, there is increasing use of medications to terminate the pregnancy due to fetal death or fetal anomalies. Objectives: To study the safety and efficacy of pregnancy termination using vaginal misoprostol in women undergone a single lower segment cesarean section. Patients and methods: This clinical trial study included 100 women (attending the Department of Gynecology and Obstetrics, Benha University hospitals) with one previous lower segment cesarean section who were advised to terminate their pregnancy (after 13-26 weeks) due to intrauterine fetal death or fetal structural anomalies. They were divided into two equal groups Group I (cases) who had uterine scars, while Group II (control) without scars. History, clinical examination, and ultrasound imaging were performed on all patients. There were 72 hours in which the patient was given misoprostol every four hours via the vaginal route. Results: It was found that the induction-to-abortion period was much shorter in the control group than in the cases group despite no significant differences in age, parity, gestational age, or doses required to induce abortion between the two groups. There were non-significant differences between patient group I with uterine scar and control group II without uterine scar regarding doses needed, except for 1-4 doses and 9-12 doses which exhibited significant differences. Conclusion:In women who have had a previous cesarean section, the vaginal route of misoprostol in a dose of 50 µg /4 hours is safe and successful for inducing a second-trimester abortion.