Background:
Pathogenic microorganisms are ubiquitous, and the potential of transferring harmful microorganisms in hospitals has always been a worry. Many studies have concluded that white coats worn by physicians and nurses, as well as other hospital clothes, may have a role in the transfer of dangerous microorganisms in hospitals. Many types of clothing and equipment, including stethoscopes, otoscopes, thermometers, and physicians’ white coats, have been identified as potentially pathogen-carrying.
Materials and Methods:
This cross-sectional study was conducted in a tertiary care setting, where all participants were informed about the study and offered the option to provide informed consent as well as complete a questionnaire. The participants have accepted and provided informed consent as well as questionnaire. The study comprised 100 aprons from health-care workers (interns, PG students, UG students, and faculty).
Results:
Males and females made up 27% and 73% of the study’s total participants, respectively. Students made up 80% of the participants, whereas professors made up 20%. Only 11% of those who took part in the study had the practice of switching aprons. Distinct species grew in 85% of aprons’ chests, 81% of aprons’ pockets, and 65% of aprons’ sleeves. Gram-positive bacteria were the most common species discovered on aprons. Gram-negative microbes were also identified in small amounts from several aprons.
Conclusion:
Aprons can be a cause of cross-contamination, hence, wearing aprons in nonclinical places such as the cafeteria, classroom, and library should be prohibited to prevent bacterial contamination carried by health-care workers’ aprons.
Background:
Several research have looked at the significance of SNPs in inflammatory mediator genes and their link to preeclamptic pregnancies, but the results have not been conclusive enough to explain why SNPs in inflammatory mediator genes may increase the risk of preeclampsia. The goal of this study is to analyze the IL5RA SNPs in order to learn more about the possible link between preeclampsia and inflammatory genes.
Materials and Methods:
A total of 304 pregnant participants were a part of this prospective observational case-control study, out of which 152 had preeclampsia, and the other 152 participants had normotensive pregnancies. The “polymerase chain reaction-restriction fragment length polymorphism” method was used to genotype SNP rs163550.
Results:
The commonness of the IL5RA rs163550G allele has been linked to an increased risk for preeclampsia with P value: 0.0230 and odds ratio: 0.6818 (95% confidence interval: 0.489–0.9505).
Conclusion:
A prominent association among the IL5RA rs163550 SNP and preeclampsia in comparison to nonpreeclampsia has been observed in the study. The study stands first to report IL5RA Polymorphism association with the pathogenesis of preeclampsia's among the Indian population.
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