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In conclusion, proper care and good hygiene of the normal mature neonatal skin are essential to maintain skin barrier function and overall health. This is achieved by optimizing epidermal barrier integrity that includes: bathing and using emollient; preventing and managing infections and skin injury; minimizing transepidermal water loss (TEWL); minimizing heat loss and percutaneous absorption of toxins. Baby bath products as well as baby wipes are safe to use and do not appear to affect an infant's skin barrier integrity. It is therefore sensible to use cleansers that have been specially designed for baby's skin, which are pH neutral and very mild to avoid irritant dermatitis and allergic dermatitis.

Platelet-rich fibrin (PRF), a second-generation platelet concentrate, was developed for the purpose of overcoming the limitations of Platelet-rich plasma (PRP). PRF can produce a higher cumulative release of growth factors than PRP. Also, this release is slow and prolonged, making it ideal for tissue regeneration and growth stimulation. This study was conducted to evaluate the efficacy of fluid PRF either alone or combined with needling versus PRP in the treatment of atrophic acne scars. A comparative study including 30 patients with atrophic acne scars who were divided into two equal groups. Group I included 15 patients in which the left side of the face was treated with intradermal injection of PRP while the right side was treated with combined needling with PRP. Group II included15 patients in which the left side of the face was treated with intradermal injection of fluid PRF while the right side was treated with combined needling with fluid PRF. All patients received four sessions with 3 weeks interval. The acne scars significantly improved in both sides of face in both groups. According to quartile grading scale and patient satisfaction; the therapeutic response was significantly higher in PRF group than PRP either alone or combined with needling. The combination with needling increases efficacy of PRF and PRP. Fluid PRF is highly effective, safe and simple procedure that can be used instead of PRP in the treatment of acne scars.

Background: Human papilloma virus (HPV) could contribute to warts and prevalence of warts is estimated to be from 7 to 10 percent of population. Immunity system could recognize bacterial, fungal as well as viral antigens. Researchers got benefit of this through development of antigen immunotherapy intralesional management. Purified protein derivative (PPD) is an intralesional immune-treatment for warts that has shown promising results. Objective: To determine whether intralesional PPD is effective and safe in common warts management. Patients and methods: The study involved twenty patients. History taking, general exam, and complete dermatological exam were performed on each patient to determine the type and number of warts, as well as the size and location of each wart in every patient. Without any pre-sensitization, all patients were then given PPD injection of 0.1 ml into the largest wart every two weeks for a maximum of six treatment sessions, or until the wart was completely cleared. The effectiveness of the treatment was determined by the size and number of warts. PPD injections were also evaluated for patient satisfaction and side effects. There was a follow-up evaluation for wart recurrence six months after the end of the treatment. Results: After 1/3 sessions, the mean of wart size reduction was 11.25 ± 14.67 whereas after 2/3 sessions the mean was 29.80 ± 28.72. After all sessions, the wart size reduction ranged from 0 -100 with a mean of 55.55 ± 42.65. 35% of patients had complete wart clearance, 20% had a moderate response, and 40% had an inadequate response, 5% showed marked response. Conclusion: Common warts can be treated with intralesional immunotherapy using PPD, which is a safe, effective, and tolerable treatment modality.