Persistentantimicrobial drugs treatmenthas resulted in antimicrobial resistance in fungi. There is always a gap for newer antifungal agent. As fungi are associated with multiple health risks in humans and many diseases in crops as well.Objective: To find alternate natural antimicrobial agent as compared to the synthetic one. Method:Essential oil of Trachyspermumammi was isolated, fractionated, and subjected to GC-MS analysis. Components from fractions were derivatized to check their antimicrobial potential against fungal resistant strains. Results:Analysis showed γ -terpinene (39%), α-phellandrene (1.3%), α-pinene (0.5%), Sabinene (0.15%), β-pinene (4.40%),  β-myrcene (1.14%), O-cymene (15.78%),  p-cymefne (38.78%), and other components were less than 1%. Fractional components were derivatised and their antifungal action was studied. Conclusion: Ajwain oil components found to be good against resistant fungal strains. While some derivatives showed more and some less antimicrobial action.

Family apiaceae, an important source of bioactive compounds, used for the treatment of many diseases since ages. Objective: Present study was conducted to explore active components of  Cuminum Cyminum essential oil. Endeavor of the current study was to investigate the phytochemical contents and antibacterial assessment of essential oil against gram positive and negative bacteria. Method: Essential oil was extracted from seeds by hydrodistillation, dried and stored at -4oC. physical and chemical characterization was done. Antibacterial activity was also determined. Results: GC-MS analysis revealed major components cuminal 35%, γ-terpinene 32%, α-terpinene-al 7%, γ-terpinene 4.45%, daucene 4.3%, and trans-caryophyllene 5.342%, some trace components like myrcene 0.12%, 1-8 cineole, and γ-terpinene-7-al were also present. Conclusion: Chemical components (cuminal, turpentine, daucene, caryophyllene) present in cumin essential oil is responsible for its biological activities.

Family apiaceae, an important source of bioactive compounds, used for the treatment of many diseases since ages. Objective: Present study was conducted to explore active components of  Cuminum Cyminum essential oil. Endeavor of the current study was to investigate the phytochemical contents and antibacterial assessment of essential oil against gram positive and negative bacteria. Method: Essential oil was extracted from seeds by hydrodistillation, dried and stored at -4oC. physical and chemical characterization was done. Antibacterial activity was also determined. Results: GC-MS analysis revealed major components cuminal 35%, γ-terpinene 32%, α-terpinene-al 7%, γ-terpinene 4.45%, daucene 4.3%, and trans-caryophyllene 5.342%, some trace components like myrcene 0.12%, 1-8 cineole, and γ-terpinene-7-al were also present. Conclusion: Chemical components (cuminal, turpentine, daucene, caryophyllene) present in cumin essential oil is responsible for its biological activities.