Introduction: SARS-Cov-2 first appeared in Wuhan, China, in December 2019 and spread all over the world soon after that. Given the infectious nature ofSARS-CoV-2, fast and accurate diagnosis tools are important to detect the virus. In this review, we discuss the different diagnostic tests that are currently being implemented in laboratories and provide a description of various COVID-19 kits. Areas covered: We summarize molecular techniques that target the viral load, serological methods used for SARS-CoV-2 specific antibodies detection as well as newly developed faster assays for the detection of SARS-COV 2 in various biological samples. Expert opinion: In the light of the widespread pandemic, the massive diagnosis of COVID-19, using various detection techniques, appears to be the most effective strategy for monitoring and containing its propagation.
Anosmia is a prevalent and pathognomonic symptom in patients with Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), often accompanied by changes of taste or dysgeusia. It is also one of the symptoms that lasts the most even after the recovery. The studies that examine the migration path and timing of SARS-CoV-2 are needed in order to determinate the ideal timing for realizing an MRI so as to possibly find an abnormal signal on the olfactory bulb.
The case of 21-year-old man with an asthma history from childhood presenting severe respiratory distress associated with a right lower thoracic pain has been studied. The non-contrast Computed Tomography (CT)-chest scan showed a basal ground-glass opacity (GGO) of the right lung leading to suspicion of COVID-19’s pneumonia. However, the molecular RT-PCR test and blood serology were negative while laboratory analyses revealed high levels of D-dimers (D-D). In addition, two repeated COVID-19 tests were negative. A thoracic CT angiography was disclosed due to the persistence of pain at the lower right thoracic side and hemoptysis that shows a bilateral distal pulmonary embolism with a right-sided basal subsegmental ischemia. We discuss a fortuitous discovery of pulmonary embolism associated with peripheral basal ground-glass opacities similar to radiological manifestations of SARS-CoV-2 pneumonia.
artery embolism; CT chest angiography; Covid-19; ground-glass opacity; pneumonia; chest pain
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