Purpose: To investigate the relationship between blood parameters and platelet-rich fibrin (PRF) membrane size for ocular graft. Methods: Total of 12 New Zealand white rabbits, 6.5 ml of blood samples was taken for each rabbit, including 5 ml for platelet-rich fibrin membrane production using L-PRF protocol (centrifugation at 2700 rpm for 12 minutes) 1.5 ml for evaluation of blood parameters. Measurement of blood parameters consists of fibrinogen, haemoglobin, hematocrit, red blood cell (RBC), white blood cell (WBC) and platelet. Measurement of the platelet-rich fibrin membrane area was done using a calibrated photograph and ImageJ software. The Pearson correlation coefficient (r) was used to evaluate each scattergram statistically. Results: Linear regression analysis found a significant positive effect on the PRF membrane area on the fibrinogen (r = 0.802, p = 0.02), WBC (r = 0.625, p = 0.03) and platelet (r = 0.839, p = 0.001). However, there was no apparent correlation to haemoglobin (r = 0.514, p = 0.087), RBC (r = 0.548, p = 0.065) and hematocrit (r = 0.454, p = 0.138). Conclusions: The area of the PRF membrane has a positively significant relation to the fibrinogen, WBC and platelets. The data in this study can be used to estimate the size of the PRF membrane as an ocular graft.

Introduction: Intraocular foreign bodies (IOFBs) are defined as intraocularly retained, unintentional projectiles that require urgent diagnosis and treatment to prevent blindness or globe loss. Case Presentation: We report a case of IOFB due to occupational accidents. In this case, there were delays in extraction considering the health facilities and conditions related to COVID-19 infection. Initially, the patient underwent closure of the entrance wound, which was performed within the first 24 hours post-trauma. However, although there was no endophthalmitis, visual acuity at the end of the observation still showed an unexpected outcome. The patient was followed up for three months after IOFBs extraction. The timing of IOFBs removal depends on several factors, including the patient’s overall health status, the nature of the injury, and the composition of the IOFBs. The postoperative examinations focus on complications such as endophthalmitis, postoperative retinal detachment, proliferative vitreoretinopathy (PVR), and sympathetic ophthalmia. The numerical values can then be used to predict the expected visual acuity using the ocular trauma score system. Conclusions: Many factors could affect the outcome quality of visual acuity. Primary wound closure, foreign body extraction, and anatomic reconstruction of the holistic ocular should be performed as soon as possible. Delay in definitive treatment was thought to affect worsening prognosis due to tissue proliferation and the tendency for severe complications, including endophthalmitis.

Introduction: Tertiary care centers often manage pediatric orbital tumors, especially in advanced lesions and complex management. We report a case of a young boy with a malignant orbital tumor involving intracranial infiltration. Case presentation: A four-year-old boy had proptosis on the left eye for two months accompanied with blurred vision, pain, and oftenly bleeds with ipsilateral nasal congestion. There was no history of trauma, eye disorders, systemic diseases, or growth disorders.  The physical examination showed stable vital signs, however a weak general condition and no enlarged regional lymph nodes. Visual acuity of the left eye was no light perception. There was a mass with protrusion of the left eye, swelling of the eyelid with an irregular surface, and a tendency to bleeds. The cornea was hazy with partly scarring, so we could not evaluate the posterior segment. MRI of the head presented a malignant soft tissue mass of the left orbital region with intracranial infiltration. The patient was given adjuvant chemotherapy; however, he could not survive due to systemic complications. Conclusions: The definitive diagnosis for the orbital tumor is obtained by histopathological examination. The investigation with CT scan or MRI imaging could be considered if not possible. However, since the definitive diagnosis still not assessed, the management can be affected. It is essential to have a definitive diagnosis to provide adequate treatment for the patients. Delayed and inadequate management can make malignant orbital tumors potentially life-threatening.