Coronal oblique dimension of spleen >12 cm is highly sensitive and shows good positive predictive value in diagnosing splenomegaly but has poor specificity and negative predictive value. Ideally, splenic index calculated using the CC, width, and thickness is the most reliable measurement for diagnosing splenomegaly. But if single measurements are to be used for identifying splenomegaly, craniocaudal length >9.5 cm, width of >10.6 cm, and coronal oblique dimension >12 cm may be used.