Aim:The aim of this study was to investigate the morphological and functional features of the process of spermatogenesis in the testes of male albino rats when exposed to lead acetate.Materials and Methods:Using histological, morphometric and statistical methods explored the effects of lead acetate on the process of spermatogenesis in the testes of male albino rats. Investigations were carried out using a digital microscope Axio Imager. M2 and automatic cell counter Countess™.Results:It is shown that when exposed to lead acetate a decrease in the production of all populations of spermatogenic cells, decreased spermatogenesis index and an index of relaxation (tension spermatogenesis), the increase in the index of ripening, index meiotic activity and germinative index, which indicates a decrease in the functional activity of the testes. On preparations, it is possible to see that after the influence of acetate of lead the head of spermatozoa becomes more roundish, breaks of tails observed.Conclusion:Lead acetate reduces the productivity of the seminal glands, which leads to the decrease of the concentration of spermatozoa, and their viability. The results of the studies suggest a negative impact of lead acetate in the course of the process of spermatogenesis in the testes of male white rats.

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The spermatogenic epithelium Spermatogenous cells Interstitial tissue (the interstitium) a b s t r a c t Introduction: The necessity of studying the peculiarities of the structural organization of the testes is determined by its participation in performing important functions for the body e making spermatozoa and the production of male sex hormones. Despite the presence of works devoted to the study of the peculiarities of the structural organization of the testes, many questions remain unresolved or require clarification. Materials and methods:As a biological test object used white Mature rats male Wistar rats at the age of 2 months. Seminal glands of male rats were used as a trial material for study. Tissue samples was investigated using a digital microscope Axio Imager.M2 (ZEISS, Japan) with software for image analysis AxioVision SE64 Rel. 4.8.3 and ZEN 2011. When sightseeing microscopy studied morphological features of the structure of the testes, and then determined their morphometric parameters. Results: Found that in rats-males aged 2 months in the testes, the proportion of interstitial tissue to the area of convoluted seminiferous tubules is about 1:30. It is shown that in the period of puberty of male white rats the highest percentage of the total amount of the spermatogenic cells are Mature male sex cells e spermatozoa. Second in quantitative terms are male stem cells spermatogonia. Discussion: Development and sexual differentiation of the testes is a complex process. The most important indicator of the structural and functional development of the testis is characteristic of the spermatogenic reservoir. The obtained results clearly demonstrate the maturity of experimental animals.