Diseño del estudio: Estudio transversal comparativo. Participantes: La población de estudio fueron todos los estudiantes matriculados en los grados de 5° a 9° de las instituciones educativas del Departamento de Antioquia durante el año 2013. Para la selección de la muestra final se realizó un muestreo polietápico, para una muestra final total de 3.222 estudiantes. Mediciones principales: Se evaluó la funcionalidad familiar mediante el instrumento APGAR familiar y la prevalencia de la Intimidación escolar a través del cuestionario CIE A abreviado, conformado por tres categorías de evaluación: victimización por intimidación, sintomatología asociada a la Intimidación escolar como ansiedad, depresión, estrés postraumático y también efectos sobre autoestima y, finalmente, el tercer componente, intimidación por respondientes, el cual explora variables sobre formas de violencia por parte de las personas que realizan acciones de intimidación escolar a otros pares. Resultados: El 46 % de los escolares con riesgo alto de bullying, el 43 % con riesgo medio y el 25 % con riesgo bajo, tienen disfunción familiar moderada a grave. A su vez, la disfunción familiar grave está fuertemente asociada con el riesgo de intimidación escolar en los escolares de Antioquia, denotando con ello que los escolares expuestos a disfunción familiar tienen menos estrategias para relacionarse, sin utilizar la agresión. Conclusiones: Las relaciones estrechas entre los miembros de la familia se encuentran fuertemente relacionadas con las estrategias de vinculación, que permiten afrontar situaciones conflictivas en diversos escenarios, entre ellos el de mayor demanda en la vida cotidiana de los adolescentes, como lo es el escolar. Por tanto, con el acompañamiento decidido de la familia, podría pensarse que los niños y adolescentes resuelvan las situaciones de agresión escolar con estrategias diferentes al bullying.
Objetivo. Determinar la relación entre clima escolar, funcionalidad familiar e intimidación escolar en estudiantes de Antioquia (Colombia). Método. Se encuestaron 2421 estudiantes, con edades comprendidas entre los 9 y los 18 años, que asistían a instituciones educativas en las nueve subregiones del departamento. Los instrumentos utilizados fueron la Escala de Clima Escolar, APGAR familiar y CIE-A abreviada. Resultados. Los análisis multivariados y de regresión logística binomial encontraron que en los estudiantes antioqueños que reportaron un clima escolar inadecuado tienen una probabilidad de riesgo de presentar alta intimidación escolar cuatro veces mayor, mientras que la probabilidad de riesgo medio de intimidación es tres veces mayor, frente a los jóvenes que reportaron una percepción de un clima escolar adecuado. A su vez, el reporte de disfunción familiar indicó asociación con un clima escolar inadecuado. Conclusión. Se evidenció no solo una estrecha vinculación entre la percepción de un clima escolar inadecuado y la aparición de la intimidación escolar en este contexto, sino que la funcionalidad familiar es la base fundamental para resolver las di fi cultades que en el día a día se presentan en el ambiente escolar.
Background:Pulmonary involvement is common in Systemic Lupus Erythematosus (SLE) patients with varying degrees of parenchymal, vascular, and pleural compromise. In GLADEL, pulmonary involvement was reported in 28.4% of the cohort, but its occurrence ranges between 30-90% due to diversity in populations and the methods used to define it.Objectives:To describe the immune-serological profile of a Colombian cohort of SLE patients and to establish its association with pulmonary manifestations.Methods:Retrospective analysis of observational data from the follow-up of a cohort of adult patients with SLE. We included 559 patients that fulfilled the SLICC 2012 classification criteria with at least 6 months of disease history and being treated in a rheumatology specialized medical center between 2015 and 2018. The immuno-serological profile was characterized, and pulmonary involvement was monitored for 1 year. Diagnosis of pulmonary involvement was performed with the rheumatologist report in the clinical chart. Prevalence of pulmonary manifestations and immune-serological profile was determined, and logistic regression was performed afterward adjusted by age, sex, and level of education to establish the association between pulmonary manifestations and a positive auto-antibodies profile.Results:The median age of the cohort was 45 years, 96.5% were female. Pulmonary involvement was documented in 113 patients (20.5%) at the beginning of the study. Their frequency was: pleuritis (14.3%), lupus pneumonitis (3.6%), pulmonary hypertension (3.2%), interstitial lung disease (ILD) (2.3%), pulmonary embolism (2.3%), lung fibrosis (2.14%), alveolar hemorrhage (1.4%), shrinking lung (0.2%). At 1 year of follow up. there were no statistically significant differences in the frequency of pulmonary manifestations. As for the immune-serological profile, there were positive ANA in 92%, anti-dsDNA in 53.1%, anti-B2GP IgM 15.2%, anti- B2GP IgG in 17.2%, and ENA in 97.2%; as for the ENA 41.7% had positive anti-RNP, 40.2% anti-Ro, 36.4% anti-SM and 16.5% anti-La. Low complement levels was characterized as follows: C3 53.1% and C4 29.2%. In the logistic regression adjusted by age, sex and level of education, there was an association between anti-SM and pulmonary manifestations with an adjusted OR of 1.85; 95% CI 1.13-3.01.Conclusion:An association between anti-SM positivity and pleuro-pulmonary manifestations was found. In other cohorts with a greater size, anti-La and anti-RNP have been associated with pulmonary involvement (OR 2.51; 95% CI 1.39-4.57 and OR 1.32; 95% CI 1-1.75 respectively). Anti-RNP positivity has been associated in particular with ILD, pulmonary hypertension and shrinking lung. Although these manifestations prevalence was similar in our cohort, an association with this antibody was not found (OR 1.01, 95% CI: 0.2-4.9). This could be explained by the smaller sample size. As for anti-La positivity, its prevalence in our cohort was less than what was found in the GLADEL cohort (16.5% vs 24.3% respectively). It is possible that this could explain the poor association between anti-La positivity with the presence of pulmonary manifestations in our study compared with those of the GLADEL cohort. There are data that indicates that anti-SM and anti-RNP simultaneous positivity is related mainly to pleuritis OR 1.98 (95% CI: 1.31-3); and this kind of involvement was found to be more frequent in our study. Our results suggest an association between positive anti-SM and pulmonary manifestations in Colombian patients with SLE, pleuritis in particular.References:[1]Haye Salinas MJ, Caeiro F, Saurit V et al. Pleuropulmonary involvement in patients with systemic lupus erythematosus from a Latin American inception cohort (GLADEL). Lupus. 2017;26(13):1368–77.[2]Emad Y, Gheita T, Darweesh H, Klooster P, et al. Antibodies to extractable nuclear antigens (ENAS) in systemic lupus erythematosus patients: Correlations with clinical manifestations and disease activity. Reumatismo. 2018;70(2):85–91.Disclosure of Interests:None declared
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2025 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.