Objectives: this observational study aimed to describe the discrepancies identified during
medication reconciliation on patient admission to cardiology units in a large
hospital.Methods: the medication history of patients was collected within 48 hours after admission,
and intentional and unintentional discrepancies were classified as omission,
duplication, dose, frequency, timing, and route of drug administration. Results: most of the patients evaluated were women (58.0%) with a mean age of 59 years,
and 75.5% of the patients had a Charlson comorbidity index score between 1 and 3.
Of the 117 discrepancies found, 50.4% were unintentional. Of these, 61.0% involved
omission, 18.6% involved dosage, 18.6% involved timing, and 1.7% involved the
route of drug administration. Conclusion: this study revealed a high prevalence of discrepancies, most of which were
related to omissions, and 50% were unintentional. These results reveal the number
of drugs that are not reincorporated into the treatment of patients, which can
have important clinical consequences.
Mapping the components of the pharmacist-led discharge counselling studies through a scoping review allowed us to reveal how this service is performed around the world. Wide variability in this process and poor reporting were identified. Future studies are needed to define the core outcome set of this clinical pharmacy service to allow the generation of robust evidence and reproducibility in clinical practice.
Objective:To measure length of hospital stay (LHS) in patients receiving medication reconciliation. Secondary characteristics included analysis of number of preadmission medications, medications prescribed at admission, number of discrepancies, and pharmacists interventions done and accepted by the attending physician.Methods:A 6 month, randomized, controlled trial conducted at a public teaching hospital in southern Brazil. Patients admitted to general wards were randomized to receive usual care or medication reconciliation, performed within the first 72 hours of hospital admission.Results:The randomization process assigned 68 patients to UC and 65 to MR. LHS was 10±15 days in usual care and 9±16 days in medication reconciliation (p=0.620). The total number of discrepancies was 327 in the medication reconciliation group, comprising 52.6% of unintentional discrepancies. Physicians accepted approximately 75.0% of the interventions.Conclusion:These results highlight weakness at patient transition care levels in a public teaching hospital. LHS, the primary outcome, should be further investigated in larger studies. Medication reconciliation was well accepted by physicians and it is a useful tool to find and correct discrepancies, minimizing the risk of adverse drug events and improving patient safety.
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