Porosity and surface area analysis play a prominent role in modern materials science, where 123 their determination spans the fields of natural sciences, engineering, geology and medical 124 research. At the heart of this sits the Brunauer-Emmett-Teller (BET) theory,[1] which has been 125 a remarkably successful contribution to the field of materials science. The BET method was 126 developed in the 1930s and is now the most widely used metric for the estimation of surface 127 areas of porous materials.[2] Since the BET method was first developed, there has been an 128 explosion in the field of nanoporous materials with the discovery of synthetic zeolites,[3] 129 nanostructured silicas,[4–6] metal-organic frameworks (MOFs),[7] and others. Despite its 130 widespread use, the manual calculation of BET surface areas causes a significant spread in 131 reported areas, resulting in reproducibility problems in both academia and industry. To probe 132 this, we have brought together 60 labs with strong track records in the study of nanoporous 133 materials. We provided eighteen adsorption isotherms and asked these researchers to 134 calculate the corresponding BET areas, resulting in a wide range of values for each one. We 135 show here that the reproducibility of BET area determination from identical isotherms is a 136 largely ignored issue, raising critical concerns over the reliability of reported BET areas in 137 the literature. To solve this major issue, we have developed a new computational approach 138 to accurately and systematically determine the BET area of nanoporous materials. Our 139 software, called BET Surface Identification (BETSI), expands on the well-known Rouquerol 140 criteria and makes, for the first time, an unambiguous BET area assignment possible.

Porosity and surface area analysis play a prominent role in modern materials science, where 123 their determination spans the fields of natural sciences, engineering, geology and medical 124 research. At the heart of this sits the Brunauer-Emmett-Teller (BET) theory,[1] which has been 125 a remarkably successful contribution to the field of materials science. The BET method was 126 developed in the 1930s and is now the most widely used metric for the estimation of surface 127 areas of porous materials.[2] Since the BET method was first developed, there has been an 128 explosion in the field of nanoporous materials with the discovery of synthetic zeolites,[3] 129 nanostructured silicas,[4–6] metal-organic frameworks (MOFs),[7] and others. Despite its 130 widespread use, the manual calculation of BET surface areas causes a significant spread in 131 reported areas, resulting in reproducibility problems in both academia and industry. To probe 132 this, we have brought together 60 labs with strong track records in the study of nanoporous 133 materials. We provided eighteen adsorption isotherms and asked these researchers to 134 calculate the corresponding BET areas, resulting in a wide range of values for each one. We 135 show here that the reproducibility of BET area determination from identical isotherms is a 136 largely ignored issue, raising critical concerns over the reliability of reported BET areas in 137 the literature. To solve this major issue, we have developed a new computational approach 138 to accurately and systematically determine the BET area of nanoporous materials. Our 139 software, called BET Surface Identification (BETSI), expands on the well-known Rouquerol 140 criteria and makes, for the first time, an unambiguous BET area assignment possible.

Porosity and surface area analysis play a prominent role in modern materials science, where their determination spans the fields of natural sciences, engineering, geology and medical research. At the heart of this sits the Brunauer-Emmett-Teller (BET) theory,[1] which has been a remarkably successful contribution to the field of materials science. The BET method was developed in the 1930s for open surfaces but is now the most widely used metric for the estimation of surface areas of micro- and mesoporous materials.[2] Since the BET method was first developed, there has been an explosion in the field of nanoporous materials with the discovery of synthetic zeolites,[3] nanostructured silicas,[4–6] metal-organic frameworks (MOFs),[7] and others. Despite its widespread use, the manual calculation of BET surface areas causes a significant spread in reported areas, resulting in reproducibility problems in both academia and industry. To prove this, we have brought together 60 labs with strong track records on the study of nanoporous materials. We provided eighteen already measured raw adsorption isotherms and asked these researchers to calculate the corresponding BET areas. This round-robin exercise resulted in a wide range of values for each isotherm. We demonstrate here that the reproducibility of BET area determination from identical isotherms is a largely ignored issue, raising critical concerns over the reliability of reported BET areas in micro- and mesoporous materials in the literature. To solve this major issue, we have developed a new computational approach to accurately and systematically determine the BET area of nanoporous materials. Our software, called BET Surface Identification (BETSI), expands on the well-known Rouquerol criteria and makes, for the first time, an unambiguous BET area assignment possible.

Se estudia el efecto de la aplicación de una crema a base de extracto de caracol en 38 pacientes con cicatrices e injertos de quemaduras en cabeza, cuello y manos, atendidos en la Unidad de Terapia Ocupacional del Centro de rehabilitación de La Corporación de ayuda al niño quemado COANIQUEM. La crema actuaría favoreciendo la despigmentación de cicatrices de quemaduras e injertos, en menor cuantía mejoraría la textura de la piel en injertos.

Introduction: Overactive bladder (OAB) is a problem with bladder-storage function that causes a sudden urge to urinate. The urge may be difficult to stop, and overactive bladder may lead to the involuntary loss of urine (incontinence). It represents a health disorder that in recent decades has become important because of its implications on the lives of those affected. It has a prevalence of 35% in women over 18 years, increasing this figure with increasing age; it can also affect men, but with a lower prevalence. There are multiple consequences of OAB: sexual dysfunction, increased risk of falls, mood disorders and an overall decreased quality of life. The identification of the main affected areas, is the first step in establishing a plan of action to improve the quality of life of people with OAB. Methodology: a review of databases: Web of Science, Psycinfo, Scopus and Theseus, from 2002 to 2014, on the influence of overactive bladder in the quality of life. Results: the main affected areas are: sexuality, performing daily activities, psychological (anxiety and depression) and sleep disorders. Conclusions: a special attention from healthcare professionals about OAB is needed. It would also be desirable to establish plans for prevention and intervention to reduce the consequences of the OAB and lessen their impact on the quality of life. Keywords: overactive bladder, quality of life, sexual life Resumen Introducción: la vejiga hiperactiva (VH) es un problema con la función de almacenamiento de la vejiga que causa una repentina urgencia de orinar. El impulso puede ser difícil de parar, y puede conducir a la pérdida involuntaria de orina (incontinencia). Representa un trastorno de salud de reconocimiento médico y social y, en las últimas décadas, ha cobrado importancia debido a sus implicaciones en la vida de los afectados. Tiene una prevalencia del 35% en mujeres mayores de 18 años, incrementándose la prevalencia a medida que aumenta la edad; puede afectar también a hombres, pero con una menor prevalencia. Son múltiples las consecuencias de la VH: disfunciones sexuales, incremento del riesgo de caídas, trastornos del estado de ánimo y una disminución general de la calidad de vida. La identificación de las áreas más afectadas en las pacientes con VH, es el primer paso para establecer un plan de intervención que ayude a solucionar los problemas mejorando la calidad de vida de las personas con VH. Metodología: revisión bibliográfica de las bases de datos: Web of Science, Psycinfo, Scopus y Teseo desde el año 2002 hasta el 2014 sobre la influencia de la vejiga hiperactiva en la calidad de vida. Resultados: las áreas más afectadas en la calidad de vida son: sexualidad, realización de las actividades cotidianas, aspectos psicológicos (ansiedad y depresión) y alteraciones del sueño. Conclusiones: se necesita una especial atención por parte de los profesionales sanitarios sobre la VH. Asimismo, sería conveniente establecer planes de prevención, así como de intervención para disminuir las consecuencias de la VH y...