Cattle leukemia is a biological and socio-economic problem of Russian livestock production and is recognized as a potentially dangerous disease for humans. Currently, cattle leukemia is diagnosed in almost all countries of the world. Rate of infection in Russian herds varies from 10 to 70% in different regions and age categories. According to state veterinary report, leukemia was registered in 68 subjects of Russian Federation in 2016. Only Leningrad, Vologda, Arkhangelsk region and Stavropol region have recovered from leukemia. The paper outlines studies carried out in the farms of the Kemerovo region, in particular studies on the resistance of cattle to the leukemia virus, taking into account the age and physiological condition; impact of conditions, seasons on infection and incidence of cattle leukemia virus; features of the polymorphism of the BoLa-DRB3 gene in cattle herds of the Kemerovo region.

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The situation of the development of dairy goat breeding in the world and in Russia is considered. Interest in goat milk as an object of functional nutrition is noted. The history of dairy goat breeding in Russia is described. It is shown that this country does not have a single domestic breed of dairy or meat goats. It is emphasized that the majority of dairy goats in the Russian Federation are local outbreed goats, but many territories are interested in purebred breeding and have favorable conditions for the development of goat breeding. The research materials were the results of a generalization of the experience of foreign and domestic goat breeders. Alpine, Nubian and Czech goat breeds have been identified as promising. These breeds are still rare for the country and characterized by high productivity. It is important to carry out selective work and have state support for the development of the industry. Despite the good prospects for the development of industrial dairy goat breeding, the basis will be farms and personal households in the near future. It is advisable to create associations of goat breeders at regional levels, as well as at the all-Russian level with international relations, for training farm specialists and all interested goat breeders in techniques for breeding work, technology for keeping and feeding animals, which will help to increase their professional level and develop the industry in general.

The purpose of the current work is to study the hereditary determination of the resistance of the black-and-white Holsteinized cattle of Kuzbass to bovine leucosis virus. The studies were carried out on the basis of the Research Laboratory "of Biochemical, Molecular Genetic Studies and Farm Animal Breeding" of Kuzbass State Agricultural Academy. Cattle genotyping according to BoLA DRB3 was carried out on blood samples by polymerase chain reaction (PCR) followed by analysis of restriction fragment length polymorphism (RFLP). The studied population of cattle demonstrates a predominant distribution of alleles associated with susceptibility to leucosis and neutral disease -88.5%, with sensitivity alleles prevailing -44.9% versus to 43.6% neutral. The frequency of the desired alleles associated with resistance to leucosis disease is only 11.5%. The frequency of genotype resistance to Bovine leucosis virus is 18.18% in general, and the genotypes that do not carry resistance alleles and carry susceptibility alleles are 62.04%.