We developed a novel foveal contour grading method to assess retinal contour in ERM eyes before and after surgery. In eyes with ERM and no foveal depression, the majority did not regain foveal depression following surgery even though retinal thickness improved.
Background and Purpose:
The sensitivity of contrast enhanced 3D FLAIR has not been assessed in patients with idiopathic intracranial hypertension (IIH). The purpose of this study was to evaluate whether hyperintensity of the optic nerve/optic nerve head on contrast enhanced 3D FLAIR imaging is associated with papilledema in patients with IIH.
Materials and Methods:
A retrospective review was conducted from 2012 to 2015 of patients with clinically diagnosed IIH and age and sex matched controls who had MRI imaging with CE 3D FLAIR. Two neuroradiologists graded each optic nerve/optic nerve head on a scale of 0-3. This grade was then correlated with the Frisén scale, an ophthalmologic scale used for grading papilledema from 0 (normal) – 5 (severe edema). To estimate the correlation between the MR and Frisén scores Kendall's tau coefficient was calculated.
Results:
46 patients (3 males, 43 females) with IIH and 61 controls (5 males, 56 females) with normal MRIs were included in this study. For both eyes, there was moderate correlation between the two scales (OD: T=0.47, 95%CI= (0.31,0.57), OS: T=0.38, 95%CI= (0.24,0.49)). Inter-reader reliability for MR scores showed high inter reader reliability (OD: K=0.76 95%CI= (0.55,0.88), OS: K=0.87 95%CI= (0.78,0.94)). CE 3D FLAIR imaging correlates with the Frisén scale for moderate to severe papilledema and less so for mild papilledema.
Conclusion:
Hyperintensity of the optic nerve/optic nerve head on CE 3D FLAIR is sensitive for the detection of papilledema in patients with IIH which may be useful in a setting where prompt diagnosis is crucial.
Purpose: This work compares best-corrected visual acuity (BCVA) and central retinal thickness (CRT) outcome measures following pars plana vitrectomy (PPV) with and without internal limiting membrane (ILM) peel for epiretinal membrane (ERM). Methods: A retrospective cohort study was conducted of 114 eyes of 114 patients with visually significant ERM undergoing PPV with membrane peel (PPV/MP) at a single institution. CRT measurements were collected from Heidelberg and Zeiss spectral-domain optical coherence tomography imaging units. Results compared preoperative and postoperative CRT and BCVA among patients with at least 60 days of follow-up. Results: A total of 114 eyes with ERM met the inclusion criteria. Eighty-one eyes (71%) underwent PPV/MP with ILM peel and 33 eyes (29%) underwent PPV/MP without ILM peel. There was no statistically significant difference between preoperative CRT between the 2 study groups ( P = .95). The mean follow-up time of eyes undergoing PPV/MP without ILM peel and with ILM peel was 391 days and 319 days, respectively. There was no statistical difference in the mean reduction of CRT between the 2 groups ( P = .470). Both groups had improvement of BCVA following surgery and there was no statistical difference in final logMAR visual acuity when comparing the 2 groups ( P = .738). Conclusions: There was an overall improvement of CRT and BCVA among patients undergoing PPV/MP for ERM with or without ILM peel. There was no statistically significant difference in the final BCVA or CRT between the 2 groups.
In this retrospective, interventional case report of a 40 year-old woman with Stickler Syndrome, we present a novel use of dermis fat graft to manage an externally exposed scleral buckle that was refractory to other methods of management. Dermis fat graft is a relatively robust material that can be effectively utilized to rescue an exposed scleral buckle. This case presentation conforms to the tenets of the Declaration of Helsinki and is Health Insurance Portability and Accountability Act compliant. This single patient case report was institutional review board exempt as it does not meet the definition of human subjects' research.Keywords: Scleral buckle; Stickler syndrome; Dermis fat graft; Retinal detachment
SummaryWe describe a novel use of dermis fat graft to successfully manage a repeatedly exposed scleral buckle that was refractory to conventional management in a woman with Stickler Syndrome.
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