Serial IVUS of the distal RA revealed a significant increase in IMV and decreases in LV and VV. Diabetes was the most powerful independent predictor of the percentage change in IMV of the distal RA after TRI. The percentage change in IMV was significantly positively correlated with HbA1c.

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However, most reports compared data from the 1990s, when guideline-based management had not been developed, with date from the 2000s, when management prevailed. Hence, the prognostic information for AMI in the 2010s, when an evidence-based therapeutic strategy was established, remains to be elucidated. In particular, data from the late 2010s are limited. One may infer that the prognosis of AMI during the chronic period in recent clinical settings could have improved further due to the widespread use of conventional evidence-based therapeutic agents, new PCI devices (e.g., new-generation drug-eluting C ardiovascular diseases are a universal healthcare issue because they are the leading cause of death worldwide. 1 Acute myocardial infarction (AMI) accounts for the major burden of all cardiovascular diseases. With the development of guidelines, evidence-based therapeutic strategies for AMI, such as early primary percutaneous coronary intervention (PCI) and optimal medical therapy, have been implemented mainly in Western countries since the 2000s. 2,3 Because of this, significant improvements in the prognosis of AMI during the acute and chronic periods have been observed in some coun-