Key Clinical MessagePanniculitis is rarely seen in polymyositis. To the best of our knowledge, we report the first case of panniculitis which precedes the antisynthetase syndrome.

Ultraviolet (UV) radiation is a major cause of photoaging 1 and photocarcinogenesis of both melanoma and non-melanoma skin cancers. 2 A variety of methods have been suggested to reduce UV-associated skin damages. 3 The World Health Organization (WHO) recommends limiting time of outdoor activities in the midday sun and keeping away from sun-reflective areas such as sand and snow to limit UV radiation to the skin. Sun protective barriers such as garments, sunglasses, hat, umbrella, and sunscreen are also recommended for UV protection. 4 Among all of these approaches, sunscreen is one of the most popular methods worldwide although the efficacy of different sunscreen types can vary drastically. Theoretically, sunscreens reduce UV-induced damage by forming a film or coating on the surface of stratum corneum that absorbs and/or scatters UV photons. Previous studies have reported factors which are affecting the efficacy of wearing sunscreen. Types of UV filters and adequately labeled sun protection

Coronavirus disease 2019 (COVID‐19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). The spectrum of symptomatic infection ranges from mild to critical with multiple severe complications. Many vaccines have been developed to prevent COVID‐19 disease, including an mRNA vaccine. Different adverse effects were reported as delayed large local reactions, swelling, erythema, urticarial, and morbilliform rashes. Among these, bullous reactions from the vaccine are considered rare. Here, we described a local bullous reaction after an mRNA booster vaccination in a post‐COVID patient.

COVID-19 is a worldwide pandemic disease that caused respiratory symptoms and severe complications. The mRNA vaccine were developed to prevent COVID-19 disease. Here we reported a case of a subepidermal blistering eruption as a cutaneous reaction after mRNA boosted vaccination in a post-covid patient.