In the current era of the industrial revolution 4.0, students are required to have 21st century skills. The 21st century skills in question are students mastering the 4C skills, that are Communication, Collaboration, Critical thinking and Creativity skills. These four skills must be possessed by students to face the world in the 21st century. One of the current learning approaches that strongly supports the achievement of 21st century skills is STEM-based learning (Science, Technology, Engineering, and Mathematics). In supporting the interdisciplinary success of STEM in physics learning, it is necessary to have effective teaching materials, one of which is a module that students can use independently. In this case, the product developed is an integrated STEM physics e-module to improve the 21st century skills of class XI high school students. The e-module was developed using Flip PDF Professional software with reference to the plomp model. This research is carried out until the development or prototype stage. The research results obtained are the development of STEM integrated physics e-modules to improve students' 21st century skills which have been developed to be valid and practical to use in learning

Industrial revolution 4.0 requires students to have 21st century skills. 21st century skills, is everyone who master the 4C which is the means to achieve success in people's lives in this 21st century. one of the 4Cs is creative thinking skills. The 2013 curriculum actually accommodates 21st century skills and demands that students be able to compete with the wider community. a teacher must prepare the teaching materials needed in the learning process before learning activities are carried out in order to achieve learning objectives. The research method used is a review article. There are 20 national and international journal articles This study aims to determine the effect of teaching materials on students 'creative thinking skills in terms of education level, subject matter, types of teaching materials, and students' creative thinking skills. From the data analysis conducted, four research results can be stated, namely: the use of effective teaching materials for students' creative thinking skills.

Ekstrak daun ekor naga (Rhaphidophora pinnata (L.f) Schott) mengandung senyawa metabolit sekunder yang berfungsi menghilangkan rasa nyeri yaitu alkaloid, flavonoid dan steroid yang bekerja dengan cara menghambat prostaglandin. Adapun tujuan dari penelitian ini adalah mengetahui efek analgesic ekstrak etanol daun ekor naga dan mengetahui dosis terbaik dari ekstrak daun ekor naga dalam mengatasi rasa nyeri. Penelitian ini merupakan penelitian eksperimental. Dimana metode yang digunakan adalah metode rangsang kimia dan rangsang air panas. Desain penelitian Post-Test Control Group terdapat lima kelompok perlakuan (Kontrol Negatif, Kontrol Positif, Perlakuan 1,Perlakuan 2 dan Perlakuan 3). Dimana masing-masing terdiri dari lima ekor tikus putih jantan. Hasil penelitian menunjukkan bahwa ekstrak etanol daun ekor naga memiliki efek sebagai analgesik. Dimana hasil uji statistik ANOVA satu arah menunjukkan adanya perbedaan yang bermakna antar kelompok perlakuan dibandingkan dengan kontrol negatif (p<0,05). Dosis terbaik ekstrak etanol daun ekor naga adalah dosis 3 (500 mg/KgBB) dengan nilai aktivitas analgesic 86,81% untuk uji rangsang kimia dan 72,32% untuk rangsang air panas. Kemudian diikuti dengan dosis 2 dan dosis 1. Kata Kunci : Daun Ekor Naga, Ekstrak, Analgesik, ANOVA

The development of science and technology is increasing. Improving the quality of education needs to be done as a national development effort in the field of human resources. One of them is by improving it into the 2013 curriculum. The 2013 curriculum aims to improve student competence, not only in terms of student knowledge, but also equip students with skills and noble character according to the personality of the Indonesian nation. Therefore, new breakthroughs are needed in the world of education, one of which is by integrating Indonesian local wisdom in learning. This study aims to analyze the effect size on the use of integrated teaching materials that are integrated with local wisdom based on education level, learning materials, types of teaching materials and student learning outcomes. The research method used is the article review method by reviewing 20 international and national articles starting from 2010-2020. From the data analysis carried out, the use of integrated teaching materials that are integrated with local wisdom gives a significant influence based on aspects of education level, subject matter, type of education teaching materials and student learning outcomes

Revolution 4.0 requires humans to have 21st century skills. The 21st century guides human resources that are able to compete with the wider community, so the government seeks to improve human resources through education. Thinking skills that are expected to achieve optimal learning outcomes are science process skills, because with these thinking skills students will be able to build meaning and confirm their understanding of a physical concept symptom and emphasize the importance of direct experience involvement in the learning process. The learning model that emphasizes learning as a process that involves solving problems in an actual context is the Problem based Learning model. Based on the description above, it can be stated that there are several researchers who have conducted research on the effect of problem based learning models on students' science process skills. So a meta-analysis of 15 articles was carried out, there was a significant effect of the problem based learning model on students' science process skills in learning physics based on grade level, physics subject matter and student learning outcomes.