Varicella (chickenpox) is a common disease of childhood, caused by varicella-zoster virus. Postviral thromboembolism is a rare complication of varicella-zoster virus in childhood. We describe 2 children who developed lower limb deep venous thrombosis shortly after varicella infection, along with a review of 130 previously reported cases.

Osteosarcomas are the most common malignant primary bone tumors in children and adolescents. Brain metastases of osteosarcoma are very rare and carry a dismal prognosis. We report a case of chondroblastic osteosarcoma of right humerus presented with right frontal lobe metastasis in a 10-year-old girl with small pulmonary lesions.

Background: In March 2020, WHO announced Coronavirus Disease 2019 (COVID-19) outbreak a global pandemic. During this pandemic, patients with sickle cell disease (SCD) have been placed in the “high-risk” category of the population. Although there are numerous publications describing COVID-19 in adult patients, pediatric data are still limited. Observation: Herein, we report case series of 5 sickle cell disease Omani children who got infected with COVID-19; illustrating their different ways of presentation, management and highlighting the outcomes. Conclusion: Although SCD patients are considered as a high-risk group, all of the observed patients, and whose cases are reported here, have recovered. A large scale of SCD cases should be studied to reach more conclusive results.

Renal cell carcinoma (RCC) is an uncommon tumor in childhood and adolescence, and is exceptionally rare as a secondary neoplasm related to prior anti-neoplastic therapy. We report a case of RCC with Xp11.2 translocation in a 17 year old boy who is a survivor of stage 4 neuroblastoma 13 years earlier.

Wilms' tumour (nephroblastoma) is the most common abdominal malignancy in children. Extrarenal Wilms' tumour (ERWT) is rare, with limited reports in the literature. Hereby, we report a case of unilateral ovarian Wilms' tumour, which was diagnosed initially by closed biopsy and confirmed later by histopathology study of the excised tumour. We are discussing the unusual location and presentation of Wilms' tumour and showing the medical challenges in both the initial clinical impression and the pathological diagnosis. Demonstrating therapeutic plans and showing the good outcome achieved by using the classic renal Wilms’ tumour therapy protocols. Keywords: Extrarenal tumour; Wilms' tumour; nephroblastoma; Ovary; paediatric tumour.