Introduction: Polycystic ovary syndrome (PCOS) causes endocrine disorders that affect the functioning of the reproductive system and the body's metabolic system. Bowel movement disorders and abdominal pain are common complaints of PCOS patients. Few studies have been performed on the relationship between PCOS and irritable bowel syndrome (IBS), and the association between the two syndromes is unclear. Material and Method: In the study, 72 patients were enrolled at gynecology and obstetric clinic in Turkey. The control group were (n=34) and women with PCOS (n=38). IBS diagnosis was made by using Roma IV criteria. Results: The results showed that IBS prevalence was similar in PCOS (52%) and the control group (50%) (p>0.05). No statistically significant association was found between IBS-PCOS and non-IBS-PCOS in terms of gastrointestinal symptoms (p=0.685). These symptoms were associated with PCOS rather than IBS. Significant differences have been observed between IBS-PCOS and non-IBS-PCOS for fasting insulin (FI), luteinizing hormone (LH) and Homeostasis model assessment for insulin resistance (HOMA-IR) (p

Aim: The possible impact of COVID-19 infection on female reproductive system is a controversial issue. The aim of this study was to investigate the effect of COVID-19 infection on anti mullerian hormone (AMH) as a predictor of ovarian response to ovarian stimulation. Material and Method: This prospective study was conducted at a university-affiliated tertiary medical center between June 2021–February 2022. The study population included 79 reproductive-aged women (22-34 years) with COVID-19 infection. Blood samples were collected for AMH levels before COVID-19 infection and after three months of COVID-19 disease. Results: The mean age of the study group was 28.11±3.49 years. Estradiol and Luteinizing Hormone (LH) was found to be lower after three months of COVID-19 disease (p

Aim: In this study, the fertility rate of women with polycystic ovary syndrome (PCOS) and endometriosis was compared with the control group, which included women with normoresponder (NR) endometriosis. Material and Method: This is a retrospective study with control in infertile women aged 25-40, suffering from PCOS and endometriosis, referred to the infertility clinic of Medistate Hospital between September 2018- December 2020. The pregnancy outcomes of age-matched participants were compared. Results: Results did not show a statistically significant association between case and control regarding age and body mass index (BMI) (p>0.05). There was a statistically significant difference between groups regarding anti-mullerian hormone (AMH) (p0.05). Conclusion: Women with PCOS and endometriosis did not show a significant difference in terms of pregnancy outcome compared to women with NR women with endometriosis.

Aim: The aim of this study was to investigate the relationship between thyroid autoantibody and first-trimester aneuploidy results. Thyroid autoimmunity (TAI) is the most common autoimmune disorder. Patients with TAI are usually euthyroid. Thyroid peroxidase (TPO-Ab) in patients with or without thyroid dysfunction is associated with infertility, recurrent embryo implantation failure, and early pregnancy loss. The impact of TPO-Ab on first-trimester aneuploidy test results needs to be studied. Material and Method: This retrospective case-control study was conducted between December 2019 and May 2022. Patients with thyroid autoantibody positivity (n=112) were included in the study as the case group. The control group was selected from age and body mass index (BMI)-matched patients (n=130). Nuchal translucency (NT), crown rump length (CRL), pregnancy-associated plasma protein A (PAPP-A) and free beta subunit of human chorionic gonadotropin (β-hCG)) values were compared between the two groups. Results: This study included two hundred forty two age-matched (29.86±4.51) and BMI-matched (23.96±2.34) women. There was no statistically significant difference between groups in terms of free thyroxine (FT4), PAPP-A and free β-hCG (p>0.05). NT as a marker for major chromosomal defects and CRL were comparable in case and control groups (p>0.05). Conclusion: There is no statistically significant relationship between thyroid autoimmune diseases and the first-trimester aneuploidy results.

We aimed to investigate the impact of Human Papillomavirus (HPV) positivity on women's mental health and sexual dysfunction (SD). Anxiety, hopelessness, and depression were investigated in this study as common psychological problems. This prospective cross-sectional case-control study was done on 213 participants who attended gynecology clinic from February 2021 to May 2022. The Turkish version of Female Sexual Function Index (FSFI)-6 was used to measure SD in women. The Turkish version of Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), and Beck Hopelessness Scale (BHS) was used to measure depression, anxiety and hopelessness in women. According to the HPV test results, the subjects were divided into two groups: 1st group as HPV positive and 2 nd group as HPV negative. 97 women in the 1st group and 116 patients in the 2nd group were included in the study. The participants' age and body mass index (BMI) were 33.91±3.74 and 24.88±3.01, respectively. There was a significant difference between HPV-positive and HPV-negative women in FSFI total scores and all subdomains (p-value<0.05). There was a significant difference in BDI, BHS, and BAI (p-value<0.05). There was a significant correlation between the FSFI and BAI in HPV-positive group. There was a significant correlation between the FSFI and BAI in HPV-negative group. There was a significant correlation between the FSFI and BDI in HPV-negative group. The health system should support women with HPV in terms of mental health. These women are more exposed to depression, anxiety, hopelessness, and SD.