This study concerns an investigation of the corrosion behavior of 316 stainless steel, CoCrMo and Ti6Al4V alloys in simulated body conditions (ringer lactate) at 37°C by the use of Tafel plots, mixed potential and electrochemical impedance spectroscopy (EIS). Ti6Al4V alloy has the highest corrosion resistance followed by CoCr alloy. Ti6Al4V-CoCrMO was the best couple for galvanic corrosion with the minimum galvanic potential and current values according to mixed potential theory and Tafel method. It was concluded that Ti6Al4V was the most suitable material for implant applications in the human body.

The authors suggest that conventional treatments be limited to a 2-month period, and that alcohol neurolysis be applied as soon as possible to prevent lengthy pain experiences.

The Coflex device prevented excessive disc loading, but increased ROM abnormally in flexion. Neither device provided satisfactory motion preservation or load sharing in other directions.

This study investigated the relevance of a mangled extremity severity score (MESS) to the evaluation of intracompartmental pressure in injured patients. We measured intracompartmental pressures with a modification of the Whitesides method and compared these values with MESS in 27 patients after trauma. For 5 of them fasciotomy was necessary to relieve high intracompartmental pressures. In our series MESS seemed to correlate with intracompartmental pressure values (r = 0.733, P < 0.05). We conclude that the MESS system provides objective criteria in determining the risk of a compartment syndrome.

In vitro and in vivo studies have proven strontium to be an osteoinductive trace element. The effect of strontium ranelate (SR) on H(2)O(2)-induced apoptosis of CRL-11372 cells and optimization of its anti-apoptotic dose were the aims of this study. After 1 h of pretreatment with SR 1 microM, 50 microM, 100 microM, 500 microM, and 1,000 microM concentrations, CRL-11372 osteoblasts were exposed to 100 microM H(2)O(2) for periods of 6-12 h. The same experiments were repeated without H(2)O(2). The apoptotic index and viability of cells were assessed quantitatively with a fluorescent dye and qualitatively with agarose gel electrophoresis. Concentrations of 1-100 microM of SR with a 6-h treatment and only 1 microM concentration with a 12-h treatment inhibited the apoptotic effect of H(2)O(2) on cultured osteoblasts significantly (P < 0.05). SR was shown to inhibit H(2)O(2)-induced apoptosis of CRL-11372 cells in a dose-dependent manner.