Background: There is a wide spectrum of salivary gland lesions with morphological and clinical diversity which makes it a difficult task for histopathological interpretation. Tumours of salivary glands are uncommon accounting for 3-10% of the total tumors of head and neck region and less than one percent of all tumours. The aim of this study was to recognize various histomorphological patterns of salivary gland lesions, their frequency, age, gender and site wise distribution.Methods: This study was carried out from June 2015 to May 2018 in the department of Pathology, JLN Medical College and associated Group of Hospitals, Ajmer. Total 121 cases of salivary gland lesions were included. Specimens were processed and stained by Hematoxylin and Eosin stain followed by histopathological examination.Results: Out of total 121 cases, 43.8% were non-neoplastic and 56.2% were neoplastic. In non-neoplastic lesions predominant was chronic sialadenitis (50.9%) followed by mucocele (28.3%) which commonly seen in submandibular gland (47.17%). Among neoplastic cases, 79.4% were benign and 20.6% were malignant lesions. Neoplastic lesions commonly were seen in parotid (75%). Pleomorphic adenoma was the commonest benign tumour (81.4%). Mucoepidermoid carcinoma was the most common malignant salivary tumour. Benign tumours were common in third and fourth decades, whereas malignant tumours were more common in fifth and sixth decades. Male predominance was seen in overall salivary gland lesions.Conclusions: Histopathological examination is mandatory in the diagnosis of salivary gland lesions because of their wide spectrum of histomorphology.
Inclusion Criteria: Pregnant women aged between 18-35 years, gestational age between 34-40 weeks of gestation, singleton pregnancy with presence of live foetus, deliveries by either vaginal route or caesarean section were included.Exclusion Criteria: Pregnant women who did experience any complication during pregnancy like diabetes mellitus, hypothyroidism, anaemia, cardiac disease, abruption placentae, multiple pregnancies, jaundice and maternal malnutrition were excluded from study. Also women having hypertension before pregnancy were also excluded.Statistical Analysis: Descriptive statistics were used to analyse the data. They were represented as Mean+SD. The statistical difference between the means of control group and study group were analysed by using student unpaired Vandana Porwal*, Deepali Jain, Seema Gupta, Shweta Khandelwal and Neena Kasliwal Dept of Pathology, JLN Medical College, Ajmer, Rajasthan, India ABSTRACT Background: PIH also known as toxaemia of pregnancy, is a major cause of maternal and perinatal morbidity and mortality worldwide. The present study was hence undertaken to analyse the effects of PIH on placenta as these changes serve as a guide to the duration and severity of disease. Methods:A prospective hospital based study was conducted from July 2012 to July 2013 in Department of Pathology, J.L.N. Medical College, Ajmer (Rajasthan). The study was done in 60 placentae, 30 placentae from uncomplicated full term deliveries formed the "Control Group" and 30 placentae from hypertensive pregnancies formed the "Study Group". Sections were taken from placenta and processed for histopathological examination. Results:The striking villous abnormalities observed in the study group were cytotrophoblastic proliferation (83.34%), thickening of basement membrane (66.67%), fibrinoid necrosis (36.67%), obliterative endarteritis (60%), decreased villous vascularity (60%) and paucity of vasculosyntitial membranes. Conclusion:The gross abnormalities and villous lesions in PIH (p<0.001) were statistically significant. Keywords: Placenta, Pregnancy Induced Hypertension (PIH), Villous Abnormalities A-70Placental Changes in PIH Annals of Pathology and Laboratory Medicine, Vol. 04, No. 01, January -February, 2017 "t" test. A 'P-value' of less than 0.05 was considered to be statistically significant.
A case of left sided malignant pleural effusion is described in a 41-year-old male, his initial workup for primary site of malignancy was unknown but later found to have hidden squamous cell carcinoma of penis which is one of the rarest site of malignancy that metastasise to pleura. Penile carcinoma manifesting with pleural metastasis and pleural effusion as initial presentation has not been reported previously.
Introduction: Fine needle aspiration cytology (FNAC) is the commonly used test for diagnosis of thyroid swellings. FNAC is a cost-effective procedure that provides specific diagnosis rapidly with minimal complications. Based on the cytology findings, patients can be subjected to surgery, thereby decreasing the rate of surgery and its consequent complications. Aims and Objective: Study is aimed to accuracy of FNAC in thyroid as compare with histopathology and classify various cytomorphological lesions of thyroid according to The Bethesda System for Reporting of Thyroid Cytopathology (TBSRTC). Material and Methods: This prospective study was done at our department from January 2013 to June 2015. Total 411 cases presented with thyroid swelling were subjected to thyroid fine needle aspiration cytology (FNAC) and the smears were made followed by routine staining and reporting. The categorization according to the Bethesda system of reporting thyroid cytology was done. The cytological diagnosis was correlated with the histological diagnosis wherever it was available. The accuracy of FNAC for the diagnosis of nonneoplastic and neoplastic lesions was determined using histopathology as the gold standard. Results: Out of total 411 cases, 387 (94.16%) were benign, 15 (3.52%) were Follicular neoplasm, 7(1.70%) cases were malignant and 2 (0.48%) were inadequate. Most frequently encountered lesion was colloid goitre in 217 (52.79%) cases
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