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Dermatofibrosarcoma protuberans is a rare soft tissue neoplasm arising from mesenchymal cells, making up about 6% of all soft tissue tumours. Often found on the scalp, neck, trunk and extremities, it has an intermediate-to low-grade malignancy potential except the fibrosarcomatous variant (high-grade), which is more likely to metastasize than other types. Here we present the case of a 46-year-old male who presented with an erythematous swelling on his upper back. MRI scan suggested a mesenchymal mass, which was then excised. Histopathology was reported as fibrosarcomatous variant of dermatofibrosarcoma protuberans. He is receiving radiation at present.

Human immunodeficiency virus (HIV) in association with autoimmune bullous disease is a very rare entity, and the pathophysiology remains uncertain. We present a case of a 65-year-old African-American female with HIV who developed a single skin lesion on her face. Subsequently, she developed multiple blistering skin lesions throughout her body. Skin biopsy of the blistering lesions revealed bullous pemphigoid.