Background: Idiopathic generalized epilepsy is defined as seizures with a possible hereditary predisposition without an underlying cause or structural pathology. Assessment of executive dysfunction in idiopathic generalized epilepsies based on standard Indian battery is not available in the literature. Aims and Objectives: To assess specific executive functions affected in patients with idiopathic epilepsy and their association with various variables. Materials and Methods: Type of observational cross-sectional study, where clinical profile of all idiopathic epilepsy patients attending the neurology OPD was studied and their executive higher mental functions were assessed using the NIMHANS battery. Results: A total of 75 idiopathic generalized epilepsy patients were included in the study. Executive functions that were commonly found abnormal in our study were word fluency ( P ≤ .001), category fluency ( P < .001), verbal n-back ( P < .001), Tower of London ( p < 0.01), and Stroop test ( P < 0.01). Executive functions showed a significant correlation with age at symptom onset, duration of epilepsy, and in those with uncontrolled seizures. Conclusion: Patients of idiopathic generalized epilepsy according to the present study were found to have significant executive dysfunction in multiple domains. This necessitates the screening for executive dysfunctions, which if detected should prompt the clinician to initiate cognitive retraining.

To study the association of depression and anxiety in patients with chronic migraine leading to disability. Materials and methods: The index cases were obtained from patients attending the Neurology outpatient Department of JSS Hospital, who satisfied International Classification of Headache Disorder 3 beta criteria for diagnosis of chronic migraine. Patients were subjected to Hamilton depression and anxiety rating scales along with, Migraine Disability Assessment Questionnaire (MIDAS) for assessing disability. Results: A total of 60 patients were studied. The associated anxiety and depression symptoms were more prevalent in patients with chronic migraine which increases disability. As per MIDAS disability assessment 20% (n=12) had grade I disability, 13.3% (n=8) had grade II disability, 50% (n=30) had moderate disability and 16.7% (n=10) had severe disability. Conclusion: More prevalence of anxiety and depression was noted in patients with chronic migraine compared to international literature because of variations in study population. Treating co-existing depression and anxiety in patients with chronic migraine decreases disability and also progression to chronic migraine in patients with episodic migraine.