Muscle fatigue is often a result of unhealthy work practice. It has been known for some time that there is a significant change in the spectrum of the electromyography (EMG) of the muscle when it is fatigued. Due to the very complex nature of this signal however, it has been difficult to use this information to reliably automate the process of fatigue onset determination. If such a process implementation were feasible, it could be used as an indicator to reduce the chances of work-place injury. This research report on the effectiveness of the wavelet transform applied to the EMG signal as a means of identifying muscle fatigue. We report that with the appropriate choice of wavelet functions and scaling factors, it is possible to achieve reliable discrimination of the fatigue phenomenon, appropriate to an automated fatigue identification system.

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Background: Parkinson’s disease (PD) is a multi-symptom neurodegenerative disease generally managed with medications, of which levodopa is the most effective. Determining the dosage of levodopa requires regular meetings where motor function can be observed. Speech impairment is an early symptom in PD and has been proposed for early detection and monitoring of the disease. However, findings from previous research on the effect of levodopa on speech have not shown a consistent picture. Method: This study has investigated the effect of medication on PD patients for three sustained phonemes; /a/, /o/, and /m/, which were recorded from 24 PD patients during medication off and on stages, and from 22 healthy participants. The differences were statistically investigated, and the features were classified using Support Vector Machine (SVM). Results: The results show that medication has a significant effect on the change of time and amplitude perturbation (jitter and shimmer) and harmonics of /m/, which was the most sensitive individual phoneme to the levodopa response. /m/ and /o/ performed at a comparable level in discriminating PD- off from control recordings. However, SVM classifications based on the combined use of the three phonemes /a/, /o/, and /m/ showed the best classifications, both for medication effect and for separating PD from control voice. The SVM classification for PD- off versus PD- on achieved an AUC of 0.81. Conclusion: Studies of phonation by computerized voice analysis in PD should employ recordings of multiple phonemes. Our findings are potentially relevant in research to identify early parkinsonian dysarthria, and to tele-monitoring of the levodopa response in patients with established PD.