Objective: To determine the clinicopathologic factors and Ki67 expression predicting triple-negative breast cancer (TNBC). Subject and method: A descriptive study on 169 patients with breast cancer at the 108 Military Central Hospital from October 2015 to September 2020. The status of estrogen receptor (ER), progesteron receptor (PR), human epidermal growth factor receptor 2 (HER2) and Ki67 expression were examined by immunochemistry. Result: The mean age of the patients was 53.8 ± 12.2 years. The rate of tumor size larger than 2cm was 54.4% (92/169). The percentage of cases with tumor grade 2 was highest at 64.5% (109/169). The rate of axillary lymph node metastasis was 37.9%. TNBC accounted for 16.6%. The statistically significant correlation was observed between TNBC and location, tumor size, histological grade and Ki67 ≥ 14%. Conclusion: Our study suggested that the right side, histological grade 3 and Ki67 ≥ 14% were independent predictive factor of TNBC.
While research on entrepreneurial intention is popular around the world and relies mostly on data from university students, a question open to academics is: 'do working people's perceptions of their employment affect their start-up intention?'. An answer to this question would be useful for employers and other stakeholders, hence, this article aims to explore the impact of young employees' perception of their current paid jobs on their entrepreneurial intention via the mediator of job satisfaction.
Research Design & Methods:A sample of 272 working people aged 25 to 30 from all three regions of Vietnam with a structure corresponding to the whole population was used to conduct a quantitative study utilising structural equation modelling (SEM). The research model was established based on the entrepreneurship event model (EEM), the theory of planned behaviour (TPB), and the job characteristics model. Findings: Young employees' perceptions of current job characteristics (perception of work meaningfulness, responsibility, and results) positively impact their current job satisfaction. In turn, job satisfaction mediates the relationship between the perception of current job characteristics and the entrepreneurial intention of young employees, with its positive effect on the intention. Implications & Recommendations: Employers should design jobs with many opportunities for learning, and create an intra-entrepreneurial working environment to take advantage of the employees' start-up intention and keep the talents.
Contribution & Value Added:The findings of this research challenge our long-held belief that job satisfaction has a negative relationship with entrepreneurial intention. The explanation was found in the new employee generations' high need for learning opportunities. In addition, the study also investigated entrepreneurship through a new lens combined of the entrepreneurship event model (EEM), the theory of planned behaviour (TPB), and the job characteristics model and demonstrated the power of these theories.
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