Breast cancer, a prevalent form of cancer in women, presents various categories that pose challenges in defining specific treatment approaches. Immunohistochemistry, a combination of immunology and histology, has made significant advancements in identifying specific surface receptors on cancer cells. This information serves as the basis for guiding appropriate treatment regimens and predicting prognosis for patients. A survey conducted on 75 tissue samples revealed the diversity of breast carcinoma types, with the infiltrative tubular form being the most common, accounting for 73.3% of cases. By utilizing immunoassay markers on these tissues, the expression rates of ER (estrogen receptor), PR (progesterone receptor), and Her2/neu were determined to be 29.2%, 52%, and 22.7%, respectively. Classification of breast cancer based on these markers showed that the ER/PR+HER2- group accounted for 24% of cases. The ER-/PR+HER2- group accounted for 18.7%, while the ER+/PR+HER2+, ER-/PR+HER2+, and ER-PR+Her2+ groups each represented 12% of cases. The ER-/PRHER2+HER2+ group accounted for 8%, and a subgroup where all three markers were negative accounted for 22.7% of cases. Estrogen and progesterone expression showed a moderately positive correlation (0 < r = 0.445 < 0.5; p <0.05). However, the expression of Her2/neu in ER-negative tumors did not show statistical significance (p > 0.05) and exhibited a reverse correlation with r = -0.016.
In the world, about 60 species of yellow camellia have been recorded and about 50 species are known in Vietnam. Camellia vuquangensis and Camellia hatinhensis were discovered and announced in 2018 in Vu Quang National Park. These two species of yellow camellia are currently considered endemic in Ha Tinh and have not been recorded in other provinces. The present study described the morphological, ecological, distribution and regenerative characteristics of these two species of yellow camellia in Vu Quang National Park. Research results will contribute to proposing appropriate measures for conservation and development.
By conducting the study on 109 non-small cell lung cancer (NSCLC) patients at the Nghe An Oncology Hospital, we found that EGFR gene mutation is a cause of NSCLC. The average age of patients is 63.8 ± 10.6. 96.33% of all the patients have Adenocarcinoma. Using Scorpion ARMS technique for EGFR mutation identification, we found the rate of patients carrying the gene mutation was 40.37%. 55.96% of the patients are male (27.87% of those have gene mutation), 44.04% are female (56.25% of those have gene mutation). In all patients with gene mutations, 54.55% of patients carry LREA and L747-P753 delinsS mutation at exon 19. The rate of patients with the L858R gene mutation at exon 21 is 29.55%; the rate of double mutation at exon 19 and 20, 18 and 20, 18 and 21 is 9.09%. 15.91% of patients have targeted-drug-resistant gene mutation.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.