Background: World Health Organization (WHO) data collection of Escherichia coli resistant to cephalosporin generation III already confirmed in 86 countries. Incredibly high carrier prevalence rates were also widely developed in Thailand, Egypt, and China. The Faculty of Medicine's research team at Jenderal Soedirman University, Purwokerto,  discovered at the beginning of 2018 that Extended Spectrum β-Lactamase (ESBL) E. coli carriers throughout the 2015 class students were 26.8 percent.Objective: This research investigated the Prevalence and associated factors of ESBL-producing Enterobacteriaceae (EPE) asymptomatic carriers in the community.Methods: The participant fill a questionnaire, and samples were taken from rectal swabs using Amies transport medium (Labware Charuzu), and then models were analyze using HiCrome ™ ESBL Agar Base (Himedia, India). Analysis of its Prevalence and Resistance Predictors uses IBM SPSS Statistics Version 22.0 for Windows (Armonk, NY: IBM Corp).Results: The Prevalence of EPE asymptomatic carriers in the community in Purwokerto was 66.7%. In the bivariate analysis, subjects who took antacids in the last eight weeks, history of hospitalization in the previous 12 months, the habit of consuming milk, yogurt, cheese, meat, seafood, and raw vegetables did not show any significant difference. Frequent chicken and freshwater fish consumption tended to be a risk factor for ESBL-producing Enterobacteriaceae with PR 1.462, 95% CI (1.115-1.918); PR 1.666, 95% CI  (0.936-2.966); however, in the multivariate logistic regression analysis, this was not significant.Conclusion: The Prevalence of EPE asymptomatic carriers in the community in Purwokerto is 66.7%. All variables did not become any significant of ESBL-producing Enterobacteriaceae. However, ESBL remains an emerging antimicrobial resistance.

Pandemi COVID-19 pada tanggal 3 Maret 2020 telah menjangkit lebih dari 72 negara di dunia termasuk Indonesia. Jumlah kasus baru di Indonesia setiap harinya masih ditemukan dengan angka yang fluktuatif. Pandemi COVID-19 di wilayah Kabupaten Tasikmalaya masih dianggap biasa saja, dan masih banyak yang tidak mentaati protokol kesehatan.  Untuk  itu  diperlukan  upaya  pemutusan  rantai  penularan  COVID-19  yang melibatkan seluruh elemen masyarakat. Pengetahuan tentang COVID-19 ini sangat penting dimiliki oleh masyarakat sehingga masyarakat mampu untuk mengambil keputusan dalam bersikap dan berperilaku yang tepat dalam rangka memutus rantai penularan COVID-19. Tujuan penelitian ini untuk mengetahui hubungan tingkat pengetahuan dan sikap terhadap perilaku penduduk Tasikmalaya dalam menghadapi pandemi COVID-19. Penelitian ini merupakan penelitian observasional analitik dengan menggunakan pendekatan  cross-sectional.  Sampel  penelitian  ini  adalah  400  penduduk  Tasikmalaya   yang   diambil   dengan   teknik   simple   random   sampling. Pengumpulan data dalam penelitian ini menggunakan kuesioner melalui Google form. Hasil analisis bivariat antara pengetahuan dan sikap menggunakan Chi-Square 2x2 menunjukan p value= 0,00. Hal ini menunjukkan adanya hubungan yang bermakna antara pengetahuan dan sikap penduduk Kecamatan Sukaresik Tasikmalaya dalam menghadapi Pandemi COVID-19 (p value < 0,05) Hasil analisis multivariat anatara tingkat pengetahuan dan sikap terhadap perilaku, variabel yang paling berhubungan dengan perilaku dalam menghadapi COVID-19 adalah sikap (p-value 0 OR 21,589 95% C.I 10,734-43,421). Kesimpulan penelitian ini, terdapat hubungan antara tingkat pengetahuan dan sikap terhadap terhadap perilaku dalam menghadapi COVID-19 di Tasikmalaya. Variabel yang paling berhubungan dengan perilaku dalam menghadapi COVID-19 adalah sikap (p- value 0,00 OR 21,589 95% C.I 10,734-43,421).

The pandemic due to the COVID-19 virus has had a significant impact on the online learning process. The difficulty of adapting learning methods for learning outcomes at the Faculty of Medicine requires that several methods be carried out offline, taking into account the safety and security of students during the pandemic. Therefore, this activity aims to design a prevention program for offline learning within the General Sudirman University Faculty of Medicine during the COVID-19 pandemic. This activity was carried out for 112 students and staff involved in the learning process. Activities were carried out by collecting data and filling out questionnaires, screening for the use of Genose, then followed by evaluation of vaccination using a rapid antibody test. Final detection was carried out using RT-PCR. The results of our activities succeeded in detecting 15 reactive students using genose, 5 reactive using a rapid test, and 1 confirmed positive for a PCR swab, so that confirmed participants could be given health assistance and break the spread of the COVID-19 virus. ABSTRAK Pandemi akibat dari virus COVID-19 memberikan dampak yang besar terhadap proses pembelajaran secara online. Sulitnya adaptasi metode pembelajaran untuk capaian pembelajaran di Fakultas Kedokteran mengharuskan beberapa metode dilakukan secara offline, dengan mempertimbangkan keamanan dan keselamatan peserta didik selama masa pandemi. Oleh karena itu, Tujuan dari kegiatan ini untuk mendesain program pencegahan untuk pembelajaran secara luring di lingkungan Fakultas Kedokteran Universitas Jenderal Soedirman selama masa pandemi COVID-19. Kegiatan ini dilakukan kepada mahasiswa dan tendik yang terlibat dalam proses pembelajaran sebanyak 112 orang. Kegiatan dilakukaan dengan pendataan dan pengisian kuisioner, skrining penggunaan Genose, kemudian dilanjutkan dengan evaluasi dari vaksinasi menggunakan rapid test antibody dan penegakan deteksi akhir dilakukan dengan menggunakan RT-PCR. Hasil dari kegiatan kami berhasil mendeteksi 15 mahasiswa yang reaktif menggunakan genose, 5 reaktif menggunakan rapid test dan 1 yang terkonfirmasi positif swab PCR, sehingga peserta yang terkonfirmasi dapat diberikan pendampingan kesehatan dan pemutusan rantai penyebaran virus COVID-19.

Acute otitis media (AOM) remains a disease that cause major public health problem worldwide. Less information about its prevalence in Indonesia, especially in Java.  The most common bacterial causes of AOM are Streptococcus pneumoniae, non-typeable Haemophilus influenzae, and Moraxella catarrhalis. There is increasing evidence that the predominant causative pathogen in AOM is changing from Streptococcus pneumoniae to non-typeable Haemophilus influenza since the introduction of pneumococcal conjugate vaccines. This study aims to determine the prevalence of Streptococcus pneumonia and Haemophillus influenzae in AOM in primary school children in Banyumas Regency. The design of this study was cross sectional and we conducted multistage random sampling to recruit the subject. Approximately 3,574 school children in Urban Banyumas Regency were screened based on the diagnose of AOM by Otolaryngologist. The resultof this study showed that the prevalence of AOM was 4,64 % (166 children were diagnosed with AOM).  In AOM samples, the prevalence of  Streptococcus pneumonia  was found in 78,4 % by optochin test, while that of Haemophillus influenzae was found in 70,4% based on the need of  X and V factor

Purple eggplant have methanol, flavonoids, saponins, and tannins compounds which have potential as antibacterial. Escherichia coli (E. coli) is one of the germs that cause various kinds of infections and currently many are reported to have experienced resistance to a number of conventional antibiotics. The purpose of this study was to explore the antibacterial activity of purple eggplant ethyl acetate extract against Escherichia coli (E. coli) bacteria. This research is an experimental study using the microdilution method to determine the minimum inhibitory concentration (MIC) and the spread-plate method to determine the minimum bactericidal concentration (MBC). This study used various doses of purple eggplant ethyl acetate extract (5-40 mg/mL) as the treatment group and the control group that was not given purple eggplant ethyl acetate extract. Purple eggplant ethyl acetate extract has a MIC value of 20 mg/mL and a MIC value of 20 mg/mL. The percentage of inhibition of purple eggplant ethyl acetate extract against E. coli bacteria was greater with the higher concentration used. Purple eggplant ethyl acetate extract has potential as a antibacterial against E. coli