Critically sized bone defects are often compounded by infectious complications. The standard of care consists of bone autografts with systemic antibiotics. These injuries and treatments lead to donor site morbidity, antibiotic resistant strains of bacteria, and often end stage amputation. This study proposes an alternative to the autograft using a porous, hydroxyapatite (HA) scaffold evaluated with and without infection and antibiotics. Twenty‐four New Zealand white rabbits received either our HA scaffold or a pulverized autograft (PBA) within a surgically created critical‐sized defect in the femur. The two grafts were evaluated in either septic or aseptic defects and with or without antibiotic treatment. The HA scaffolds were characterized with micro computed tomography. Post‐euthanasia, micro computed tomography, histology, and white blood cells component analysis were completed. The HA had significantly greater (p < .001) mineralization to total volume than the PBA groups with 27.56% and 14.88%, respectively, and the septic HA groups were significantly greater than the aseptic groups both with and without antibiotics (p = .016). The bone quality denoted by bone mineral density was also significantly greater (p < .001) in the HA groups (67.01 ± 0.38 mgHA/cm3) than the PBA groups (64.66 ± 0.85 mgHA/cm3). The HA scaffold is a viable alternative to the bone autograft in defects with and without infection as shown by the quality and quantity of bone.

We present a rare case of complete talar extrusion after trauma. Treatment of this severe injury remains controversial as a result of the lack of congruent evidence-based literature, associated high complication rate with primary repair, and difficulty in objectively assessing long-term outcomes. Recent small sampled retrospective studies and isolated case reports have documented success with immediate reimplantation of the talus through using various health status questionnaires and serial radiographs. This case illustrates complete revascularization on 1-year follow-up magnetic resonance imaging of a completely extruded and fractured talus that underwent immediate reimplantation.

No abstract

Gentlemen, esteemed fellows, when on January 31 I made a statement to our secretary about my report, I meant to demonstrate in the Society two then just removed by an operative way of the appendix; But since that time, over the past week, we have performed 2 more such operations in the hospital, and as a result of this, today I can already demonstrate to you 4 drugs. As for the patients, from whom the drugs were received, the patients are still in bed. The patient's earliest surgery is only 2 weeks old tomorrow, and she can leave bed only 4-5 days after this period.

The patient whom I will have the honour to show you today has undergone a severe, disfiguring operation - removing the entire larynx following cancer. Without an artificial larynx, the operated patient not only cannot communicate with the people around him, but cannot make a single sound, not even a single moose that exists for example in most deaf people.