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Neurologists and paediatricians call for action on “massive” rises in the prices of orphan drugs

How large a risk is society prepared to run with the climate system? This is a question of the utmost difficulty and it admits a variety of perspectives. In this paper we draw an analogy with the management and regulation of insurance companies, which are required to hold capital against the risk of their own financial ruin. Accordingly, we suggest that discussions about how much to reduce global emissions of greenhouse gases could be framed in terms of managing the risk of 'climate ruin'. This shifts the focus towards deciding upon an acceptable risk of the very worst-case scenario, and away from how "avoiding dangerous anthropogenic interference with the climate system" has come to be framed politically. Moreover it leads to the conclusion that, in terms of greenhouse gas emissions today and in the future, the world is running a higher risk with the climate system than insurance companies run with their own solvency.

attempt to save FSS, the government risks bankrupting large sections of the British corporate sector. Other policy measures could allow greater flexibility for trustees of pension schemes and remove counter-productive legislation and encourage innovative market-based solutions to pensions problems.

Nigeria is a prime example of a developing country with ill-defined property rights. However, people still manage to save, mostly through traditional and informal means, facilitated by strong family and community institutions. This paper argues that the government should concentrate on strengthening these institutions rather than weakening them by imposing an inappropriate, Western-style, formal pensions system on the country.