Despite high prevalence, the etiopathology of melasma is not fully understood. Nevertheless, many factors have been associated with the disease, including: sun exposure, sex steroids hormones, drugs, stress, and pregnancy. The high occurrence within familiars (40-60%) suggests a genetic predisposition to the disease. This study explored, through complex segregation analysis (CSA), the inheritance model that best fit the family segregation pattern of facial melasma when accounting for the main epidemiological risk factors. We evaluated 686 subjects from 67 families, and 260 (38%) of them had facial melasma. The CSA model, adjusted for age, skin phototype, sex, sun exposure at work, hormonal oral contraceptive, and pregnancy, evidenced a genetic component that was best fitted to a dominant pattern of segregation. Melasma results from an interaction between exposure factors (e.g. pregnancy, hormones, and sun exposure) over genetically predisposed individuals.
ResumoContexto: Grande parte da produção científica apresentada em congressos não é publicada. Mesmo nos países do primeiro mundo, os números demonstram que essa perda é expressiva.
Objetivo
Conclusões:Os números revelados nessa amostra revelam o quanto a publicação das pesquisas no Brasil é relegada a segundo plano. Muitos trabalhos deixam de ser publicados pela falta de prioridade e tradição em escrever, falta de tempo, empenho e de incentivo.Palavras-chave: Pesquisa, resumos de reunião, autoria e co-autoria na publicação científica.
AbstractBackground: Great part of the scientific production presented in congresses is not published. Even in developed countries, figures show an expressive difference between presentations and publications.
In the last decade the presence of Brazilian physicians in International Meetings
of Dermatology has been expressive. In parallel it has also been expressive the
submission of poster abstracts in those Meetings. Considering the meetings from
2005 to 2013, 379 posters were presented in meetings of the American Academy of
Dermatology. Brazilian universities were the origin of 59.9%. The Brazilian
Society of Dermatology's recognized residency programs were the origin of 69.9%
of the presented posters. Considering the period from 2005 to 2010 (n = 165
posters) the papers effectively published were 19 (11.5%).
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