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Background: Compartment syndrome of the hand is a rare and devastating complication of peripheral intravenous extravasation. With changes in critical care research, vasoactive medications are now more frequently administered through peripheral lines in the acute setting. Methods: We present the case of a patient diagnosed with compartment syndrome of the hand secondary to phenylephrine extravasation in the setting of hypovolemic shock. Results: The use of fasciotomy compartment release and intraoperative phentolamine resulted in significant improvement in tissue perfusion postoperatively. Conclusion: With incraesed incidence of peripherally administered vasoactive medications, the hand surgeon should be aware of potential complications and treatment of compartment syndrome with urgent fasciotomy and phentolamine administration.

Volume 133, Number 3 (Supplement) • PSRC Abstract Supplement Saturday, March 8, 2014lipoproteoplex for topical use. There was no evidence of cutaneous inflammatory reactions grossly or in histologic analysis with either delivery system. ConClusion:Our results demonstrate that the lipoproteoplex offers an efficient and reliable route to deliver siRNA for topical gene silencing. The stability and non-toxic nature of lipoproteoplex gives it a unique advantage and makes it an ideal candidate for clinical cutaneous drug delivery.

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