Background: To study the prevalence of thrombocytopenia during pregnancy, its etiology and maternal and perinatal outcome. Methods: It was a prospective one year study of pregnancy with thrombocytopenia. The prevalence and cause of thrombocytopenia during pregnancy and its effect on maternal and perinatal outcome was studied. Result: Among 990 deliveries, 104 women were having thrombocytopenia during pregnancy. The commonest etiology was gestational thrombocytopenia (61.53%). Fetal complications were still birth (5.88%), low birth weight (14.7%), and neonatal thrombocytopenia (1.92%). Thrombocytopenia in pregnancy did not affect the mode of delivery and pre-term delivery rate. Conclusion: Gestational thrombocytopenia, preeclampsia, HELLP syndrome, malaria, ITP and dengue were the common causes of thrombocytopenia in pregnancy. Patients with GT and ITP have better maternal and peri-natal outcomes as compared to preeclampsia and HELLP syndrome.

Objective Comparison of metformin and N acetylcysteine on clinical, metabolic parameter and hormonal profile in women with polycystic ovarian syndrome. Design Prospective comparative study. Setting Obstetrics and Gynecology department in Kamala Nehru Memorial Hospital Allahabad.