Introduction: Cutaneous metastasis (CM) is an uncommon clinical presentation and poses trouble in diagnosis. However, it is remarkable and can occur due to a known or an unknown primary tumor. Despite the fact that clinical assessment helps in the diagnosis, Fine-needle aspiration cytology (FNAC) is a modest, basic, and quick principle line of investigation for the finding of CM. Materials and Methods: It was a retrospective study conducted in the department of pathology at a tertiary care teaching hospital. The study was conducted from January 2010 to May 2020. All cases of CM that has been diagnosed by FNAC were included. Results: During the study period, a total of 37 cases of CM were observed, constituting 0.15% of all FNACs. The age of the patients ranged from 35 to 74 years, and the male: female ratio was 1.05:1. Primary tumor was known in all 37 cases. Among males, lung carcinoma was the more common whereas breast was the most common organ of primary among females. The most common lesion was a single nodule (27 cases), with predominant site being chest wall (32.5%), and the most common tumor at microscopy was metastatic adenocarcinoma. Conclusion: FNAC is a fast and safe procedure that can be utilized as a first line of investigation in diagnosing metastatic skin lesions. Basic assessment of cytomorphology alongside significant clinical subtleties could help in recognizing the site of an unknown primary.
Background: Ovarian cancer is the fth leading cause of cancer related death in the USA, and has the highest mortality rate due to late diagnosis. The most common modalities used in diagnoses are B-Mode USG, Conventional MRI and DW-MRI. This study aims to statistically analyze and compare the sensitivity, specicity and measurement of agreement for these modalities. From March 2019 to September 2020, 103 pat Method: ients with ovarian masses underwent radiodiagnostic testing with USG and MRI, and subsequently 85 patients underwent surgery and the gold standard histopathological examination. The radiologic diagnosis was correlated with the histopathologic diagnosis for these patients and the sensitivities, specicities and area under the ROC curve were calculated. The Results: area under ROC curve increased in the following order: B- Mode USG < B-Mode USG & Doppler combined < conventional MRI < DW-MRI. The measurement of agreement Kappa increased in the following order: B- Mode USG < B-Mode USG & Doppler combined < conventional MRI < DW-MRI. The study showed that addition of Doppler to B-Mode USG reduced its sensitivity and NPV. Both USG and conventional MRI were found to have comparable sensitivities. While DW-MRI is superior t Conclusion: o other modalities in its high specicity in diagnosing ovarian tumors, USG has equal sensitivity and can be used for initial presumptive diagnosis in patients with suspected ovarian malignancies.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.